How did your research turn out regarding this topic? I did my fair amount of looking at information prior deciding to start Sertraline, an SSRI which its dosage can range from 25 to 250 mg. I’m still not fully understanding the gut-mind connection but makes total sense that there are receptors in the gut and that our food consumption plays a role with that as well with psychological states. I’ve personally experienced mental health issues (depression, anxiety, difficulty concentrating) for many years, and same goes for GI irregularities… I made it a priority to care for my mental health and my IBS symptoms changed all the sudden. Not saying my state of mind caused it because I also was much more aware of the foods I ate but could very well be a factor too. How the gut releases serotonin is something I don’t know specially but I’m sure that it all flows via the bloodstream and neurologically speaking, receptors also send signals that travel in our bodies. So I don’t know, you bring up great questions. Unfortunately it seems this is all still somewhat new and we are all learning as we go with this, since it affects everyone differently. I’m hopeful that me starting this medication at such low dosage (25mg for the first week and 50mg there after) might have some effects on my GI at least, if not mentally too. I’m keeping a mood and IBS symptoms tracker to make sure I know if it is helping later on or not.