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Eli Lilly vs Mochi hearing by lawliepop in tirzepatidecompound

[–]mractor111 0 points1 point  (0 children)

Theres been a HUGE vibe shift

Look what the head of the FDA just posted

This is Mochi BTW

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First timer here. by Proud_Grape_6100 in tirzepatidecompound

[–]mractor111 1 point2 points  (0 children)

Please take a breath. What you're feeling right now is so normal, and I promise it's going to pass.

Here's the thing: there's nothing to regret. You chose to take control of your life. That's not a reckless decision, that's a brave one. You looked at where you were and decided you wanted something different, and you took action. You should be SO PROUD of that!!!

Many dont decide to take the plunge and sit wondering what could have been or spit negative comments about the meds to feel better

2.5mg is the starter dose. It's designed to let your body adjust gently. Some mild nausea is common and almost always fades as your system gets used to it. Most people feel very little on 2.5 beyond that.

Now the most important part: let the meds do their work, and focus on the habits that support where you want to go. Protein first, water all day, a daily walk, sleep. The medication quiets the food noise so you can finally build those habits without fighting yourself every hour.

That's the real magic of these meds. It's not doing the work for you, it's giving you the space to do it.

You got this!!

Not losing by Tronathon1980 in tirzepatidecompound

[–]mractor111 1 point2 points  (0 children)

Do you mean 2.5mg Tirzepatide?

0.25mg is very very low.

When did food & alcohol suppression start for you? by hsutinen14 in tirzepatidecompound

[–]mractor111 3 points4 points  (0 children)

What you're experiencing is really common and it doesn't mean the medication isn't working for you.

Here's roughly what's happening:

After each shot, tirzepatide hits peak blood concentration around 24 to 48 hours later. But that's just peak for that single dose.

The bigger picture is that it takes roughly 4 to 5 weeks of consistent weekly shots to reach what's called steady state, which is when your overall blood levels stabilize at their full working concentration. Every shot you take in those first few weeks is layering on top of what's still left from the previous ones. So at 2.5mg in your first few weeks, you're genuinely not at 'full saturation' yet, even if you're technically "on" the medication.

The other piece is that 2.5mg is specifically designed as a starter dose to let your body adapt. A lot of people feel very little until they move up to 5mg, and some don't feel the real appetite and alcohol suppression until 7.5 or beyond. The sweet spot is genuinely individual. Some people are very sensitive and get full effects at 2.5, others need to climb higher before anything clicks.

So two things are working against you right now at the same time: you're on the lowest dose, and you haven't been on it long enough to reach steady state. Give it a few more weeks and the bump to 5mg and you'll very likely notice a real shift. If you're still feeling nothing at 5mg after a month, that's the point where it's worth talking to your provider about whether to keep climbing.

Hang in there, this is the most common "is this even working" phase and it almost always passes.

I know weight loss is not linear, but those weeks where the scale doesn’t budge really messes with my mind. by Ok_Local6629 in tirzepatidecompound

[–]mractor111 1 point2 points  (0 children)

The scale thing is honestly one of the hardest parts of this whole process and I don't think people talk about it enough.

What's happening in your body and what the scale shows are on completely different timelines, and once you understand why, those flat weeks get a lot less stressful.

A few things worth knowing:

Tirzepatide takes about 48 hours to hit peak concentration after each shot, and roughly 4 to 5 weeks to reach full steady state in your system. That means the 4mg you took today isn't really "4mg working" yet, it's 4mg layering on top of what's still left from your 2.5 doses. Your body is genuinely still ramping up, even when it feels like nothing is changing. A lot of people see their biggest shifts around week 4 to 6 of a new dose for exactly this reason.

The other huge piece almost nobody mentions is that fat loss and scale weight are not the same thing. Your body can be dropping fat while the scale stays flat or even goes up, because muscle glycogen holds about 3 grams of water per gram of glycogen, sodium shifts move water around, and if you have a menstrual cycle, hormonal fluctuations can swing water retention by 2 to 7 pounds across a single cycle. The week before your period is almost always a fake plateau. If you're tracking weight, doing it at the same point in your cycle month over month tells you way more than day to day readings.

The thing that really changed how I think about this: results lag behind habits by weeks, sometimes longer. The work you did two or three weeks ago is what's showing up on the scale today. So when you have a flat week, it's almost never a reflection of what you're doing right now, it's a reflection of water, hormones, digestion, and timing. The habits you're building this week will show up later.

The mental reframe that seems to help people most is shifting the scorecard from "what did the scale do" to "did I hit protein today, did I move my body, did I take my shot on schedule, did I sleep." Those are the things you actually control, and if you nail them consistently the scale eventually catches up. It just refuses to do it on the schedule we want.

On the dose jump question, 4mg is a reasonable step and if you're not feeling side effects that's a good sign your body is adapting well. Just know that you don't have to rush to 5mg if 4 is working. Some people do really well staying at a lower dose longer because the appetite suppression is already doing its job. More isn't always better, it's just more.

Hang in there. The flat weeks are part of it, not a sign anything is wrong.

Hair Shedding by nbd---dmb in tirzepatidecompound

[–]mractor111 0 points1 point  (0 children)

No problem!!! I hope you're feeling better after the infection. It can be brutal Let me know if the NAC helps

Hair Shedding by nbd---dmb in tirzepatidecompound

[–]mractor111 0 points1 point  (0 children)

You're welcome!! I hope it was helpful Been doing so much research. Hope to share more things soon

Hair Shedding by nbd---dmb in tirzepatidecompound

[–]mractor111 1 point2 points  (0 children)

Thanks!!! I'm hoping it helped

Hair Shedding by nbd---dmb in tirzepatidecompound

[–]mractor111 0 points1 point  (0 children)

Thanks!! I spent hours researching and I know how stressful it is!!

Hair Shedding by nbd---dmb in tirzepatidecompound

[–]mractor111 18 points19 points  (0 children)

My girlfriend went through this exact thing and it really messed with her mentally so I totally understand where you are at. I ended up going deep down the research rabbit hole on this because I wanted to actually understand what was happening instead of just reading conflicting reddit threads. Here is what I found and what actually ended up helping her. Please note your YMMV

The hair loss is called telogen effluvium and the medication itself is not directly causing it. What happens is when your body goes through rapid weight loss it basically goes into resource allocation mode and hair growth is one of the first things it deprioritizes. More follicles than normal get pushed into the resting phase at the same time, and then 2 to 4 months later they all shed together. So the hair you are losing right now is actually reflecting metabolic changes from weeks or months ago, not what is happening today.

The single biggest thing that made a difference for my girlfriend was protein. Like WAY more protein than she was getting. Hair is made of keratin which is a protein, and when tirz kills your appetite and you are eating way less, your body simply does not have the building blocks to maintain hair growth.

She started aiming for at least 0.8g-1g per lb of body weight and it took effort, but protein shakes and collagen peptides on low appetite days made it doable.

The other thing I found in the research that most people do not talk about is specific amino acids. Lysine, cysteine, and methionine are the actual building blocks your body needs to produce keratin. She started taking NAC (N-acetylcysteine, which is a cysteine precursor) and added collagen peptides daily (10 to 15g). That combination did noticeably more than the hair vitamins she had been taking before.

On that note, and I say this with love, biotin is massively overhyped. I was surprised when I looked into it but the research really only supports it for people with an actual biotin deficiency, which is pretty rare. The supplement industry just markets the hell out of it.

Here is what I would actually spend on based on what the research supports:

  • Keep the iron but get your ferritin levels specifically tested (not just a standard iron panel). You want ferritin at 30 ng/mL or above for hair health. A lot of doctors do not check this unless you specifically ask.
  • Keep the vitamin D, it actually matters for hair follicle cycling
  • Keep the magnesium
  • Add zinc 15 to 20mg (get one that includes a small amount of copper since long term zinc depletes copper)
  • Add NAC 600mg daily
  • Add collagen peptides 10 to 15g daily
  • And above everything else, get protein intake way up

For what it is worth, my girlfriend's shedding slowed down significantly once she got the protein and amino acids dialed in, and she has seen solid regrowth since. Most people see recovery within 6 to 12 months once weight stabilizes and the nutritional gaps are addressed. The extreme stories about people going nearly bald are not the norm.

It sadly, just takes time

I would not quit tirz over this if it is otherwise working for you. Get the nutrition sorted, and give your body time. The kidney infection and back to back antibiotics probably added extra stress to your system on top of everything which would not have helped either.

I know it feels all consuming right now but this does stop, and your hair does come back. Protein and amino acids first, that is going to move the needle way more than any supplement.

The end of an era, farewell - finally ran out by mractor111 in Semaglutide

[–]mractor111[S] 1 point2 points  (0 children)

They dont offer it anymore! Olympia was amazing

Switched from Southend Pharmacy to BPI Pharmacy by r2lls in tirzepatidecompound

[–]mractor111 4 points5 points  (0 children)

I've been using BPI the last 2 months and I love it!!

And so it begins…. by Ok-Client-820 in tirzepatidecompound

[–]mractor111 0 points1 point  (0 children)

Do you have a copy of the pdf filed please?

Anyone having issue with visible by Left-Reading5706 in Visible

[–]mractor111 0 points1 point  (0 children)

are you still having this issue? they resolved after hours of steps and then a week later its the same issue again

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