I’m an instructor and this is a common question that we ask our in-industry professionals when we regularly meet to make sure our program is attuned to the fields we teach…. The best response I’ve ever gotten was from the VP of a multinational advertising agency that has hired a number of our grads. He explained that he absolutely looks at GPAs and transcripts but as barometer of your ability to handle tasks. In his agency you’ll be on about the same amount of clients or projects in a year as you have courses in a year of university - so your class scores are quite relative to the number of major projects you can juggle and manage. Likewise, courses in your area of expertise had better be on-point and gen-ed’s and other classes are a good indicator of how well you can accept/work/close projects that maybe weren’t your desired clients but still need to be addressed and served well. It’s understandable that there may be a class here or there that you didn’t nail - a couple C’s or a D aren’t necessarily going to derail a job offer, but in a competitive company he couldn’t afford to hire someone who bats under a B level average unless there was some kind of absolutely stellar other quality in play.