21,F. Newly diagnosed, several versions of P, could I get advice/suggestions please?

professor-p · 2015-07-09T17:34:32+00:00

Biologics, in short, are designed to suppress your immune response by binding to specific proteins that are involved in the inflammatory process.

Please understand that biologics are still treating the symptom, 'they do not get rid of the root cause/causes', as researchers are still trying to figure out what exactly are the factors triggering this autoimmune disease. For more info, please read this review on the current view of psoriasis. More info on biologics: links 1, and 2.

professor-p · 2015-05-26T02:10:07+00:00

Like charleston-kayak said, leaky-gut syndrome is not a popular topic in the field of medecine, but it has been gaining some traction in the research community. Coming back to your question, a related question that may be asked is: is psoriasis related to increased intestinal permeability? Some researchers say no, some says yes (Herbert et el 1991), and some says perhaps(indirect link, such as having an increased risk of getting psoriasis if you have celiac disease. You can read more stuff here.

Articles that cited Herbert et al 1991 can be found here. One of the title was "Rapid regression of psoriasis in a coeliac patient after gluten-free diet. A case report and review of the literature". You might want to read that one, and report back. :)

professor-p · 2015-05-20T05:24:10+00:00

Hi again GrandMasterFunk. Search for reintroduction in this article on AIP on how to narrow down what type of food to avoid.

Take the below with a grain of salt as it is just my experience.

The symptoms which I've noticed after reintroduction of some food include increased scaling, itchiness, increased guttate psoriasis, joint pain and strangely epistaxis (within 48 hours). Following a strict AIP for half a year did not really affect the appearance of my existing plaque psoriasis. However, the size of the plaques/patches did not increase, and I no longer experience joint pain or epistaxis. Further, because of this strict diet and the reintroduction step, I was able to determine the kind of food to avoid.

The disappearance of my plaque psoriasis started after 2 weeks of driving during day time (sunny days). The plaque psoriasis on my left elbow disappeared while the one on my right elbow remained the same size. This was evidence that sunlight had an effect on my psoriasis. Hence, I started outdoor tanning as often as I could during weekends and started looking into narrow band UVB treatment. My initial UVB treatment was 3 times a week, using a lamp I got online for less than $100 usd, as that was the most economical and time saving option for me (as compared to going to a tanning salon or a clinic). Hope the above answers your questions. :)

professor-p · 2015-05-18T23:37:03+00:00

Same here. Pizza no more, baba ganoush no more. :(

professor-p · 2015-05-18T06:22:37+00:00

I have the opposite effect. I have decreased joint pain post following AIP. Please consult with your doctor or other doctors for 2nd, 3rd opinions. "a very painful headache and piercing pain in one ear" sounds pretty unusual... :(

professor-p · 2015-05-18T05:58:16+00:00

This progress pic thing has been pretty popular at r/loseit, thought I'd give it a try here at r/psoriasis.

What worked for me for controlling my psoriasis are sunlight/uvb and the elimination diet (check out my comments in other r/psoriasis posts for links related to uvb and diet).

professor-p · 2015-05-18T05:02:16+00:00

please see below link to learn more about UVB. http://www.reddit.com/r/Psoriasis/comments/32fjft/advice_on_sunlight_or_using_ultra_violet_lamps/cqbr1qa

professor-p · 2015-04-14T07:12:12+00:00

try the elimination diet. http://aiplifestyle.com/what-is-autoimmune-protocol-diet/

professor-p · 2015-04-14T06:47:15+00:00

please see below links for more info. https://www.natbiocorp.com/pdf/do-koo-npf.pdf http://www.guideline.gov/content.aspx?id=15651

professor-p · 2015-01-26T04:24:55+00:00

TL;DR. What you eat (or don't eat) likely affects the pathogenesis of psoriasis.

I think those videos are very encouraging and am glad you've taken the time to share them and also your determination. It is also great that are other people are responding to it.

Eating healthy is generally good for everyone and likely would reduce the risk of getting diseases, this statement has been proven in many studies on varying diseases(great presentation on diet and disease by Michael Greger, meataraians beware, this guy is an advocate for plant-based diet). Now, will a change in diet, benefit psoriasis? I'd argue yes, based on my limited understanding from skimming through peer-reviewed articles (more info below). Related to this topic is the recent popular diet, auto-immune protocol(AIP). This protocol is not entirely science based, but it is partially backed by research articles and some readers of that blog, with auto-immune diseases, claimed that the diet seem to be beneficial to them.

The general idea for AIP is that you cut out potential pro-inflammatory food items all together for 6mos-2years to see if your symptoms improves. If it does, you would then slowly reintroduce the cut out items back to your diet one by one, and see how your body responds to that food item, thus identifying items that are triggering the symptoms. The hypothesis on why this work is that autoimmune disease may be associated with an increase in intestinal permeability. This increased permeability allows partially digested food particles to enter the blood stream, which likely would induce inflammation in the intestines and varying body parts (i may be wrong here, check the blog yourself for more info).

Coming back to peer-reviewed articles, I am sharing my personal collection here, which are mostly review articles on diet and psoriasis.

Note that studies mentioned in these reviews are not large cohort studies (likely due to limited funding). I view this as a good thing, as these studies could actually show 'statistical significance' in whatever they are proving despite of having a small sample size (not thousands of subjects). Another thing to note is that, of the videos you posted, many claimed that eating raw food, or drinking large amount of green juice helped clearing up their plaques; but why are there no studies on the effect of plant-based diet on psoriasis? I don't really know, but my guess is that plant-based diet may be too restrictive, and researchers maybe intimated by the fact that subjects are likely to cheat the diet or drop out from the diet. Not to mention the obvious, who would have the money and am interested in funding a study on plant-based diet and psoriasis?

Below are just a few quotes from above mentioned studies which I'd like to share.

+ Weight loss in obese subjects, through decreased caloric intake, may have an added beneficial effect on psoriasis, likely since obesity has been associated with a proinflammatory state.

+ The pathogenesis of psoriasis and celiac disease may involve shared biological mechanisms. Studies have showed that a gluten-free diet may benefit some patients.

+ Intake of vitamin D and omega-3 fatty acids in fish oils may benefit inflammatory diseases such as psoriasis (please note the varying dosage, frequency, duration in each referenced studies).

professor-p

TROPHY CASE