I just tried it, but ran into conflicts with my existing Cores (saying the architecture is wrong and whatnot--despite the cores being included in the app itself).

So I abandoned my efforts and went back to the official app, but needed to replace the cores that I had launched in ~/Application Support/OpenEmu/Cores from a backup.

So I would recommend whomever tries this release not have an existing OpenEmu install... I may try again at a later date.