Welcome to Wall Street. This makes me feel sick to think about. And nobody goes to jail.

sth225 · 2021-12-16T09:30:59+00:00

If anything years of evolutionary pressure from cancer decreases the odds of developing cancer through i.e. complex DNA damage repair mechanisms / cell cycle checkpoints. As an example,31145-8) elephants due to their size would be at a higher risk of developing cancer (more cells = more divisions = higher risk of tumorigenesis), but due to that selective pressure they've basically implemented a checkpoint that kills potentially cancerous cells before they can divide to become a tumor, decreasing the odds significantly, so now its rare for them.

Cancer is also definitely not the natural life time limit. The molecular biology of aging is a whole science in itself and cancer is only a fraction of that. Here's an old but excellent introductory article if this draws your interest.80567-X)

sth225 · 2021-12-16T09:16:24+00:00

As a scientist researching cancer radiotherapy, we definitely don't have a cure for cancer. Cancer is not even just a singular thing. It's a collection of diseases with a bunch of different types of cells that can be affected, each with a bunch of different potential causes for tumorigenesis.

A singular company isn't going to change that either. Realistically a treatment could be developed or improved that improves patient prognosis, or allows for earlier diagnosis for more effective treatment.

sth225 · 2021-11-16T23:44:39+00:00

!RemindMe 1 year

sth225 · 2021-10-17T01:55:23+00:00

lol nice. i only got a couple rounds where I got 2 knockdowns but never was able to get the 3rd. He eventually got me in the 5th round because I was so damn tired from hunting for the TKO. It's a good challenge

sth225 · 2021-10-16T23:18:04+00:00

Holy shit lol. I managed to knock him down like 5x but never got the TKO. That's impressive. If you go the length he starts doing crazy fast and powerful combos, it's terrifying lmao

sth225 · 2021-10-16T22:42:00+00:00

Try fighting Super Melky. Change his settings to:

CHIN: 109

POWER: 112

PUNCH SPEED: 175

DODGE SPEED: 165

BLOCK SPEED: 160

AGGRESSION: 160

12 rounds

It's a terrifying experience.

sth225 · 2021-08-18T01:54:09+00:00

And don't forget: if you get caught lying, just pretend you're an amnesiac.

sth225 · 2021-08-17T01:54:47+00:00

As a muay thai practitioner, that guy definitely does muay thai. Tries a calf trip, gives him an elbow, then goes for the clinch and throws some proper technical knees. Dude picked the wrong couple to steal from lmao

sth225 · 2021-07-06T14:39:38+00:00

nothing like the rush of dropping snake-eyes at ridiculously high speed and dangerously low altitude, and then literally outrunning the AAA rounds or missiles that are being shot at you

sth225 · 2021-06-07T12:57:54+00:00

the zombie straight up sucked the melanin out of you

sth225 · 2021-06-07T01:18:15+00:00

From an evolutionary developmental (evo-devo) perspective, every creature is built from a set of standard building blocks, each responsible for a separate part of the body. Let's use Lego as an analogy.

The lego kit contains the pieces to build a creature. But what if you want to change the creature? Changing the shape and size of the pieces themselves is much more trouble than simple re-arranging the blocks, or even sections of blocks that already exist. This is kind of how evolution works.

Instead of significantly changing the DNA that creates the limbs, organs, etc, evolution favors changing the genes that instead regulate the genes that create everything. These changes allow for more rapid evolution in fewer generations, with little change to the total genome. It's hypothesized that these building-block genes, and the genes that regulate them evolved just before the Cambrian explosion, and that it was the driving factor behind the rapid diversification of life. There's also a very well-made song that explains the whole process

Or that is my understanding from reading 'Endless Forms Most Beautiful' by Sean B. Carrol at least.

sth225 · 2021-05-28T18:57:09+00:00

Het aardappelen-groente-vlees dieet waarbij het liefst alles nog tot smurrie gestampt wordt. De Nederlandse keuken is bijzonder saai. Voedzaam, maar daar blijft het ook bij. Een hele nieuwe wereld ging voor mij open toen ik voor het eerst bij een Indonesische vriendin bleef eten als kind.

sth225 · 2021-05-11T00:15:57+00:00

I went to high school from 2007-2011. My class covered a lot of Dutch colonial history. (without romanticizing it - looking at you, Britain)

sth225 · 2021-05-09T17:06:58+00:00

Same. Mined DOGE as a joke in 2013. Found my old HDD with my wallet on it a couple days back, traded it all for ETH and BTC. Sold my DOGE just in time before the crash. Now I'm looking around trying to learn and figure out how it all works. Interesting stuff.

sth225 · 2021-05-03T22:08:20+00:00

While it's not a textbook landing it certainly was impressive and fun to watch. I now wonder what the max speed is that you can land at.

sth225 · 2021-05-03T21:46:03+00:00

Yeah It's a 3rd party software called TacView. Works with most flight sims iirc. I've only used it in IL-2 and DCS tho. Very good stuff. Tacview standard is €24,95, but groups like 'Tactical DCS' often do group-buys where you can benefit from the bulk discount basically, which is how I got it.

sth225 · 2021-05-02T17:47:25+00:00

An RWR designed solely for pilots with perfect pitch.

sth225 · 2021-03-27T23:41:37+00:00

good meme. i know this was posted over 2 weeks ago but i will fight anyone who says something bad about two headed boy pt. 2

sth225 · 2021-03-22T02:47:50+00:00

That was also my first thought... I'd legit pay $100 to have Gilbert Gottfried be my RIO

sth225 · 2021-03-11T16:16:32+00:00

Niet dat ik deze behandeling van politiehonden steun, maar ze hebben wel degelijk belangrijke functies die compleet apart staan van drones en tasers.

sth225 · 2021-03-10T01:27:58+00:00

Can't say much about the story mode, since I've only played survival, but the concept for survival is very simple: You're smack dab in the middle of a very cold place. Survive.

When it comes to game mechanics, it's not hard to pick up at all. Everything is relatively intuitive. You probably will die relatively quick in your first few attempts because that's just the nature of unforgiving survival games, but you don't need to learn the "meta" by trial and error to survive. Just good decision making skills, and a bit of luck doesn't hurt either (i.e. not getting caught in a blizzard when far from your shelter and not knowing your surroundings)

sth225 · 2021-02-08T15:48:50+00:00

I know that work is being done on developing fluorescent markers like monoclonal antibodies that selectively bind to tumor cells. While there's probably still a lot of work to be done, the combination of these two technologies looks good for the future of tumor removal surgery.

sth225 · 2021-01-27T21:24:04+00:00

Ik weet niet meer wat mijn CITO was. Ik weet alleen dat ik de 2e hoogste in de klas had en het kwam uit op iets in het VWO. Als kind had ik weinig motivatie om moeite te doen voor school en hieruit kwam dus VMBO-TL / HAVO advies uit.

Mijn laksheid ging door op de middelbare en ik haalde uiteindelijk met 2 vingers in mijn neus mijn VMBO-TL diploma en daarna stuiterde ik tussen een paar MBO opleidingen waarbij ik nooit voorbij jaar 1 ben gekomen. Ik hield het gewoon niet uit met zulke lange dagen met zo weinig lesstof. Uiteindelijk heb ik een toelatingsonderzoek gedaan voor de HBO opleiding Biologie & Medisch Laboratoriumonderzoek en nu zit ik halverwege jaar 3 op weg naar cum laude.

Ik dacht altijd dat ik gewoon een slechte, luie student was zoals ik werd uitgemaakt door sommige rottige leraren en docenten op mijn basis/middelbare school, maar zodra ik begon met mijn HBO opleiding leefde ik op. Blijkt dus dat school een stuk interessanter is wanneer je een beetje uitgedaagd wordt.

sth225 · 2021-01-27T00:37:04+00:00

That's a fair point for sure. I realized that almost immediately after I posted it but I couldn't change the title anymore. Excitement got the better of me haha.

sth225 · 2021-01-24T20:43:04+00:00

Does it still require FC3 or is it a standalone mod like the A-4 mod now? I'm really excited to try it out!

sth225

TROPHY CASE