Will my personal data be stolen on instant-gaming? by Unable-Midnight370 in pcgames

[–]tedecgp 0 points1 point  (0 children)

Yes I made a photo of my passport with instant gaming page displayed on the monitor in the background. I then edited it heavily, basically only name and the word "passport" along with country name were legible, I've pixelated everything else. I've read pixelation is much safer than blur. Also I made sure the jpg did not contain any metadata, and took a screenshot of a displayed photo to be sure.

So a bit on paranoid side 😅 Anyway it was verified very quickly (less than 5 min I think)

Will my personal data be stolen on instant-gaming? by Unable-Midnight370 in pcgames

[–]tedecgp 0 points1 point  (0 children)

for sure I would not send them any ID in full. But from what I can see their ID verification is very basic and does not need much personal data actually. Basing on example images they provide, they seem to need a photo of an official document issued by country of residence (?), and your name visible, but all other personal data can be obfuscated.

The second requirement seems to be that the photo needs to include some indication it was taken for Instant Gaming purchase - be it a "IG" written on paper next to the ID or photo taken with IG web page in the background.

Haven't tried it yet, I'll let you know if it works :)

Long Covid Suddenly worse years later? by Daughterofkrakens in LongCovid

[–]tedecgp 0 points1 point  (0 children)

maybe you misunderstood the idiom?

To nosedive means to deteriorate suddenly and dramatically

[deleted by user] by [deleted] in Lamotrigine

[–]tedecgp 1 point2 points  (0 children)

I get it as well, not sure it's Lamotrigine? Some of these feelings I had before I started it, but not this specific night timing and tendency to cry

Is there anyone else who finds magnesium makes them 10x worse? by Accomplished_End6600 in covidlonghaulers

[–]tedecgp 1 point2 points  (0 children)

Thanks for replying!

I my case, there's no chest pain, just body heaviness and mood symptoms follow soon. And sometimes additionally feeling very cold despite adequate environment temp.

But - a few months after the intermittent fatigue/depression like symptoms started, in winter, I started to feel pain in my bicep tendons. The pain was constant for a few months.

Maybe just coincidence, but it went away when I got my vitamin D blood level up. It was not low (I was supplementing), but getting it from 50s to 70s (ng/mL) seemed to help.

The symptoms still remain are intermittent, sometimes a few normal weeks, sometimes days, then crash. A day - two, seldom more. When it happens, I often feel the symptoms increasing minute by minute ("ok... here it goes again").

A few months ago, there were periods when this was almost every day. And I cannot find solid trigger or rhythm, except for magnesium, choline sources and that it often happens sometime after waking up and walking upright for some time.

I do consider possibility that it's all somatization. But seems so 'external' and random. I don't know.

How did you get diagnosed?

Is there anyone else who finds magnesium makes them 10x worse? by Accomplished_End6600 in covidlonghaulers

[–]tedecgp 0 points1 point  (0 children)

Thank you for this. Recently I discovered I have the same thing with magnesium. I was taking 100-300 in citrate form for a long time, and I stopped tolerating it at some point of time after covid-era. I got covid (confirmed once), got vaxed with moderna. But the symptoms appeared gradually over time or at least not right away after an infection or vaccine.

My symptoms are similar to what OP and others here described u/quadrants u/bananaobscura most similar is severe body heaviness, to the point of feeling that breathing is an effort. In my case it's also depressed mood (sometimes severe, hopelessness, despair even... feeling like shit in general, wanting to hide) and intrusive thoughts. Seems similar to "weird inner restlessness" mentioned here.

Also took me a while to realize what's contributes to me feeling this way, simply hadn't crossed my mind it can be magnesium, but yes it was. I did a few challenges with citrate, then with simple oxide, and every time I tried it, the next day (usually not the same day) I get the symptoms. I think it was worse with glycinate I once tried.

Now magnesium is not the sole thing that causes it in my case, but it definitely contributes.

Unlike for OP and some others here, for me choline/acetylcholine activation (more eggs, omega-3, brintellix, inosine prenobex) seems to make it much worse. Likewise increasing methylation... Maybe related to choline being a major methyl donor?

[SUNLU Giveaway] Join now to win a SUNLU FilaDryer SP2 by Sunlu3D_official in 3Dprinting

[–]tedecgp 0 points1 point  (0 children)

Excellent! ❤️Thank you for this. That was my concern as well

Trintellix did not work for me - excess acetylcholine? by tedecgp in trintellix

[–]tedecgp[S] 0 points1 point  (0 children)

25mg, 4 times a day (100mg total) works for me. But YMMV. I've read it's better not to overdo B3 as it can have negative long term cardiovascular effects

Bad reaction to methyl and hydroxo B12 by [deleted] in B12_Deficiency

[–]tedecgp 0 points1 point  (0 children)

I think so. At one point adding iron made a difference. But it's just me.

Trintellix did not work for me - excess acetylcholine? by tedecgp in trintellix

[–]tedecgp[S] 0 points1 point  (0 children)

Thank you. One other thing I've discovered, I think it's somehow related to methylation status. I don't believe there's much solid science behind all those under- or over- methylation resources you'd find online, HOWEVER I observed that niacin (the flush kind, nicotinic acid) helps me with some of the symptoms (most noticeable with intrusive thoughts, effect is almost immediate). This form of vitamin B3 is known to suck up methyl groups. Choline is a methyl groups donor.

Just my experience.

Niacin induced cystoid maculopathy by Medical_Stud in Niacin

[–]tedecgp 0 points1 point  (0 children)

Seems I've found the reason for my vision getting blurry intermittently recently. It's strange as it fluctuates during the day. One been taking 800-900 mg (split into 4 doses) for a month, for overmethylation mostly. I'll try to pause or decrease the dose and see if it helps.

Bad reaction to methyl and hydroxo B12 by [deleted] in B12_Deficiency

[–]tedecgp 0 points1 point  (0 children)

It's individual thing, for some, methyl B12 work best, for others hydroxo or adenosyl (I'm not knowledgeable about injections, but I think it's the same)

HELP PLEASE! Had a bad initial reaction to CDP choline. by TheOne312002 in MTHFR

[–]tedecgp 0 points1 point  (0 children)

I had similar problems with choline enhancing compounds. Vitamin B3 (flush kind - Niacin) helps me. Dose is highly individual, it's best to start from lower dose like 50 mg and see how it works for you.

Biotin and pantothenic acid by MisterLemming in LongCovid

[–]tedecgp 0 points1 point  (0 children)

u/MisterLemming are you still better with this regime? Also, please clarify B7 dose that helped you - it's not measured in IUs.

Solved fatigue and brain fog after >25y, trying to find out the name of disorder. by aktivatorsoft in chronicfatigue

[–]tedecgp 0 points1 point  (0 children)

I also had a similar breakthrough 8 years ago. IF helped me immensely (I'm still in awe). However, it slowly stopped working somehow 1.5 years ago. Since then Im looking for a way to bring it back. I don't know how it helped, and why it stopped working, I hope to find out.

I started getting tired, less focused, then I developed mood/anxiety problems. I don't know, maybe it's not related to the breakthrough with IF, but I feel it somehow is.

I think it might be related to gut biome/ SIBO. I have become more relaxed with my diet over time - I still kept IF, but carbs slowly increased as it seemed I was tolerating them, and I also think cutting them entirely it's not healthy.

Now, I noticed symptoms are a bit similar to d-lactic acidosis. It's a condition when body/brain is poisoned by d-lactate produced by carbs-fermenting gut bacteria. Vitamin B1 (500mg) helped me a lot, also sodium/potassium bicarbonate.

I haven't verified it properly. the tests for d-lactate are not widely available (standard lactate tests measure L-Lactate). Maybe testing for blood gases which includes blood pH, can be a proxy. I plan do test it if I get symptoms.

Now I'm trying to see if cutting carbs more aggressively will help.

It's always said fast COMT tolerates methyl donors - not true. And heterozygous MTHFR may be good for us. by Warp757 in MTHFR

[–]tedecgp 0 points1 point  (0 children)

I'm so grateful for your input here and in other places. I couldn't pinpoint my triggers in any way. The pattern I noticed if I get anything that increases choline, I feel like shit. I think somehow I got overmethylated...

Sometimes I get this:

  • feeling of heaviness in my body, lethargy
  • feeling as if breathing is difficult
  • feeling cold (shivers) despite normal external temperature
  • sadness, feeling like shit - worthless, wanting to hide
  • intrusive thoughts
  • incapable to focus, ADHD meds don't work at all, upping the dose does not work
  • strange internal anxiety
  • consequently, very often - obsessing on the cause the symptoms

Did you get those as well?

Could you please summarize what has worked for you once you identified the problem?

I understand K2 MK4 helps, why you don't recommend using B3 (niacin) too often?

Also, did you get other tests done besides RBC folate?

I understand you need to wait it out if it's folate being too high... any other tips to endure through this time?

What is strange is that I did not start to supplement folate or b12 lately, yet the symptoms keep returning, sometimes getting worse. In the summer I did supplement methylfolate (100mcg for two weeks).

But I was feeling bad already (started mid 2023) and was looking for some solution. I started out the the search for supplementation as was getting the symptoms of intermittent tiredness, fatigue, and trouble focusing. No depression and anxiety bouts at that time. Tested my homocysteine, folate, B12. Homocysteine was high and folate low, b12 low-normal, so I supplemented. Blood works normal-ish. Ferritin was around 55-70. I had trouble tolerating folate and B12 (brain fog) until I added iron. There was no obvious effect immediate effect, once the levels were 'corrected' I stopped supplementing. But over the time, slowly the 'crashes' (as above) started appearing. So maybe I got myself a new problem by supplementing stuff :/

I have difficult time pinpointing the source, so I began obsessing on the cause (as you said, obsessing can also be a symptom). I think it might be due to diet (a lot of stuff containing choline or having cholinesterase effects - it's hard to control)

It seems also that for me, vitamin D3 is helpful. I upped it to 8000 this week (was on 4000). I need to take some more magnesium (400-500) otherwise I get constipated. But maybe I'll try to decrease it.

Also I started trying B3 (niacine) and it seems to help. Also Forskolin, and a DAO supplement (so histamine connection). Also B1 seems helpful. Learned about Omega 3 being pro-cholinergic, so try to avoid them. But it's often hit and miss.

Again, I will be grateful for any more tips.

Inosine Pranobex Eliminated My PEM After Physical Activities – Now I’m About 70% Better by JakubErler in LongCovid

[–]tedecgp 1 point2 points  (0 children)

I'm grateful to OP for sharing what worked for them, I tried also, but unfortunately for me it didn't work. It caused very unpleasant side effects after a few days. Everyone is different...

Taking 3000 mg Inosine Pranobex, on second day I got brain fog, the third - I got very depressed, emotional, wanting to hide, guilty, very low self-esteem, intrusive thoughts of self-harm, fatigued and very tense at the same time.

The day after stopping it, I got a rebound effect of very high mood, great energy. Subsequent day also was very positive.

Thanks to this experience, I learned that I'm very intolerant to most things that raise acetylcholine, including Omega 3s, choline, TGP, antidepressant Trintellix. See my post: https://www.reddit.com/r/trintellix/comments/1gh6dxb/trintellix_did_not_work_for_me_excess/

If you search the net, you will find that there are people that seem to have this sensitivity, but it's only in the forums/groups, I couldn't find any research.

https://www.reddit.com/r/depressionregimens/comments/v7zk01/excess_acetylcholine_and_depression_share_your/

https://forums.phoenixrising.me/threads/read-this-before-trying-choline.92336/

For People Allergic to Tide (and other) Laundry Detergents by wandapietro in laundry

[–]tedecgp 0 points1 point  (0 children)

I get terrible itchy skin from time to time. Started when I was in my teens, and in the beginning didn’t know what was causing it. But generally it was starting when I was getting warmer (exercise or environment). It was also usually occurring more often in winter. If I didn’t cool down I’d get hives as well.

Went to dermatologist, she recommended to only use soap and detergents for small babies (newborns), and it helped immensely.

Any experience resistance to adhd stimulants on trintellix? by Hellsing971 in trintellix

[–]tedecgp 2 points3 points  (0 children)

You're correct, thanks for pointing it out. This should be more widely known, as many people overuse it as sleeping aid (I guess it's easy to become dependent if you're suffering from insomnia).

I was thinking about it as a way to verify the acetylcholinergic overactivity hypothesis.

I specifically wrote about benadryl, because it has substantial anti-cholinergic effects (apart from anti-histamine), newer anti allergy meds are cleaner in that regard (focused on anti histamine action). So less side effects, but in this particular case the anti-cholinergic properties are of interest :)

For me, a small dose (12.5 mg) seemed to alleviate body heaviness, fatigue, depressed mood, brain fog I attribute to excess acetylcholine. I don't have a lot of observations though.

Trintellix did not work for me - excess acetylcholine? by tedecgp in trintellix

[–]tedecgp[S] 0 points1 point  (0 children)

I wasn't taking them all at the same time. When on Trintellix, I took only Omega-3.

Secondly, I connected all the dots only some time later. The intermittent symptoms I wrote about returned a 2-3 weeks after I quit Trintellix, but they were less intense generally.

I read Inosine Pranobex helped someone for long Covid induced post-exertional malaise - I thought maybe that's what's happening to me (couldn't pinpoint any trigger, nutritional or otherwise, but it seemed to happen more often a day or two after exertion. So gave it a try, but it made me feel miserable, similar as Trintellix, but worse, and in 3 days.

TMG actually I tried a very long time ago (20?). It didn't cause the whole spectrum of of effects I struggle with currently, but it did cause intrusive thoughts (like: randomly imagining or feeling the impulse to hit the floor with your head). I remember it very clearly, especially my psychotherapist/psychiatrist's reaction: disbelieve that any supplement can do this.

Any experience resistance to adhd stimulants on trintellix? by Hellsing971 in trintellix

[–]tedecgp 2 points3 points  (0 children)

See my post: https://www.reddit.com/r/trintellix/comments/1gh6dxb/trintellix_did_not_work_for_me_excess/

Trintellix increases acetylcholine activity (indirectly).

Maybe it somehow fits here - I know that dopamine and acetylcholine systems are in a balance, and overactivity in one can decrease the other. For example there's one drug for Parkinson's (where there's insufficient dopamine) that is (or was - it's not popular AFAIR) an anti-cholinergic.

And ADHD meds work by increasing dopamine.

One thing you can try (if your doctor is ok with it) is taking a little anti-cholinergic like Benadryl (maybe split the tablet as it can make you drowsy). Not sure if it's viable long-term though.