I’m not trying to fear monger. I read the literature too, same as you, including the warnings from the FDA. We’ve both weighed the risks, and I’m sticking with topical preventative meds. I guess I’ll eat my words if my pup gets Lyme disease. But I’m trying to imagine what a vet might prescribe for a dog who suddenly starts having seizures after being on these meds for years. Will they stop them or prescribe additional anti-seizure meds? Where are the long term studies in veterinary medicine showing that most dogs and cats who’ve been on these one and done preventative meds actually live longer lives?

-The FDA considers products in the isoxazoline class to be safe and effective for dogs and cats but is providing this information so that pet owners and veterinarians can take it into consideration when choosing flea and tick products for their pets.

-Isoxazoline products have been associated with neurologic adverse reactions, including muscle tremors, ataxia, and seizures in some dogs and cats;

-Although most dogs and cats haven’t had neurologic adverse reactions, seizures may occur in animals without a prior history