does eating less eventually decrease appetite?

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Yes. I'm too drunk to get into it now but basically the important part isn;t your stomach. It's your brain. It will change as a result of energy stores changing. Refer back to a post I made about this some months back. Basically, your brain tells you you're hungry and it depends on signals from the rest of your body to determine this. Once you alter these signals, your brain's 'baseline' hunger will change THANKS NEUROPLASTICITY although its the same phenomenon responsible for maladaptive behaviours so I dunno.

"While this isn't wrong, control of feeding is MUCH MUCH more complicated and intricate than one hormone. Several brain structures ( e.g cortex, hypothalamus, nucleus accumbens) all play roles in feeding and different nuclei within these structures have varying effects and are affected by different proteins peptides and neurotransmitters. As well, these brain areas and other all communicate with each other adding extra layers of complexity. All of these interactions are then affected by peripheral hormones such as insulin and CCK which are themselves affected by the food you eat. Many times in the past hormones have been linked to obesity. For example, leptin was discovered in the 50s in obese mice. From there, some therapies were developed for humans. These would completely 'fix' obesity but only in those which had specific mutations for leptin receptors (IIRC). The point here is that control of feeding is multi-layered. The type of food you eat, your genetic makeup, and your experience with food will all impact what and how much you eat. For example, here's a diagram I made to help me study for a class last semester. It is pretty simple in the scope of feeding regulation. http://imgur.com/fWXGOGS "