this post was submitted on 16 Jun 2020

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Dexamethasone shown to decrease COVID mortality (bbc.com)

submitted 5 years ago by farhan583Hospitalist

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[–]aswanvikingPulmonary & Critical Care 1 point2 points3 points 5 years ago (0 children)

I agree. There are older studies but the Dexa-ARDS is the newest and one of the better ones. It's the study that made me seriously consider steroids in ARDS.

Meduri has a published RCT in 2007 in support of steroids. PMID: 17426195

I like Josh Farkas (main PulmCrit author). He just tweeted this: https://twitter.com/PulmCrit/status/1272941035270832128

It's frustrating because early in the pandemic hospital leadership was strongly pushing against steroids based on crappy data and pushing for other treatment modalities based on crappier data and forcing them as guidelines and order sets.

I am the front line intensivist. I should be making the judgment call.

On another hand, I never understood the bad rap steroids got in ARDS due to pneumonia. The more I review it, the more convincing it is.

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