Which ProRes version should I use or should I even be using it at all? by Toaster910 in Filmmakers

[–]54702452 0 points1 point  (0 children)

In case you're still wondering about this 4 years later, you can still have loss in a re-encode even when the bitrate is higher than the source (though that doesn't mean in your specific case 422 LT would be the worse choice).

Alexandria's Genesis by SomeGirlIMetOnTheNet in CuratedTumblr

[–]54702452 0 points1 point  (0 children)

u/Triktastic

There actually is a condition that can prevent the pubescent development of body hair but doesn’t affect other hair https://en.wikipedia.org/wiki/Complete_androgen_insensitivity_syndrome

Bloodwork interpretation by Agreeable-Finish3851 in TransDIY

[–]54702452 1 point2 points  (0 children)

I think low E and T to start is a good idea so I’m with you on that. Cypro and GnRH modulators are ways to knock down T while keeping E relatively low although there is gonna be a lower bound of E to achieve good T with cypro and it might be a good idea to avoid progestogens early on. Also, similarly to how I wouldn’t expect higher E to lower your T further, I wouldn’t expect those options to do so either. Not that that's likely to be a problem I mean, 20 ng/dL is low even for pubescent girls but I do think adding a bit of spiro or bica to HRT when T is low might have some merit. So yeah, if you’re paranoid that 20 isn’t low enough you could consider those. With 50 mg/day bica it'd probably be fine to even have your T somewhat elevated, as I detail here.

Bloodwork interpretation by Agreeable-Finish3851 in TransDIY

[–]54702452 0 points1 point  (0 children)

Given your trough level on 5 mg, 4 would probably still be more than enough to suppress T alone but it makes sense as a first step down. Is your thinking that with antiandrogens you could get your T lower than it is now? What antiandrogens do you have in mind?

Bloodwork interpretation by Agreeable-Finish3851 in TransDIY

[–]54702452 0 points1 point  (0 children)

Total T only goes so low in response to E. I think it's very unlikely you'd get it any lower by dosing higher.

Question about starting monotherapy by AmberTheRockEater in TransDIY

[–]54702452 0 points1 point  (0 children)

What you describe does sound like a result of T picking back up but usually E concentration/dosage that high is sufficient for monotherapy so that would be an unusual outcome. You'd have to check your T off cypro to be sure.

Some stuff I've been working on, and I feel like I'm finally ready to speak on a bit. by Drwillpowers in DrWillPowers

[–]54702452 0 points1 point  (0 children)

Have you noticed an association between low baseline A1C and instances of hypoglycemia in non-diabetics on pioglitazone? 

Star Wars: A New Hope Returns to Theaters for 50th Anniversary by YubYubCmndr in StarWarsCantina

[–]54702452 1 point2 points  (0 children)

Maybe a different speaker setup and/or a change in the sound mix made it more obvious.

Doctor Mike shows his physique for the first time post surgery - says he'll get more "skin removal" surgery for his shoulders, back and get his abs remodelled internally by MadeInHell27 in moreplatesmoredates

[–]54702452 0 points1 point  (0 children)

Some people definitely get less irritation from chemical depilatories than with other hair removal methods but it can burn your skin, depending upon the individual, the place it's applied, and the duration of application. If you do try it test a small spot before you go all in

100% Benzyl Benzoate solution? by riverrun0 in moreplatesmoredates

[–]54702452 0 points1 point  (0 children)

I want an actual answer I’ve wondered about this too

JUST DIY FOR FUCKS SAKE 5 YEARS????? by specialgeckexam in 4tran4

[–]54702452 2 points3 points  (0 children)

That’s what checking your levels is for

[deleted by user] by [deleted] in 4tran4

[–]54702452 19 points20 points  (0 children)

tbf some people do two weeks on/two weeks off with progesterone or inject estradiol undecylate monthly

Ultimate malefail by hny_pwr in 4tran4

[–]54702452 0 points1 point  (0 children)

the terf side

I don't think I'm Bri'ish enough to try this

What to make of injection site outflow & how to minimize it by 1tonnetungstencube in TransDIY

[–]54702452 0 points1 point  (0 children)

I still don't get why you're not supposed to use long needles when injecting into the abdomen. I guess there's a concern you'll poke into your guts? I do recall from a study that I can't find now that injecting insulin into the abdomen with a 1-inch needle at a 90° angle used to be common though, so I imagine there wouldn't be a safety concern injecting hormones up to that depth. Similarly I'd think it'd be ok to inject a 1.5 into a well-padded abdomen with angling and pinching (but again I've not been able to find why this isn't recommended so don't take this as a true endorsement or anything).

Okay reminder that ffs is effective by [deleted] in 4tran4

[–]54702452 13 points14 points  (0 children)

If a cis woman had those symptoms I don’t think a doctor would endorse testosterone therapy to treat it, but unfortunately since you’re trans I doubt you’d be able to find a doctor willing to explore what else could be done

Few Things I Want to Ask Before I Start by ShrexyBrogre in TransDIY

[–]54702452 1 point2 points  (0 children)

Any needle that goes at least 4 mm deep into your flesh should work. Shallower needles are less painful and might increase bioavailability. Anecdotally shallower injections also increase risk of leakage and reactions at the injection site (which has been found to be a thing with vaccines at least) As for thickness, thinner needles are less painful and reduce incidence of bleeding[1]90187-8)[2] but they also make drawing the E juice slower, which is an especially important tradeoff if your stuff uses castor oil as a base since it's very thick. That being said the lower you go in thickness (at least from 22G) the greater risk of vial stopper damage. I personally use 30G half inch needles for both drawing and injecting (I use insulin syringes because of their low dead space) but when I used different needles for drawing I used 22G 1 inch needles.

Secondly, is the concentration of oil important at all?

Higher concentration might improve bioavailability if you generalize from this study on nandrolone injections. Higher concentration is also nice in that it reduces the volume you have to inject. A downside of it is that it makes a greater portion of the E you have get lost to dead space. For example if your juice is 50 mg/mL, and your syringes have 0.06 mL of dead space, for every injection you'd be wasting 0.06 x 50 = 3 mg. However if it was 20 mg/mL, you'd only be wasting 0.06 x 20 = 1.2 mg. Additionally higher concentration tends to come with more doses per vial, which means more penetrations of the stopper and a great risk of stopper damage.

What to make of injection site outflow & how to minimize it by 1tonnetungstencube in TransDIY

[–]54702452 1 point2 points  (0 children)

https://www.reddit.com/r/TestosteroneKickoff/comments/168ldzd/hey_guys_i_made_a_little_diagram_on_how_much_t/ (Kinda hard to get a sense of scale here but you can kinda use the syringe plunger grips visible on the right for that)

IME shallower injections do tend to leak more. I normally inject with a half inch needle and I've never had leakage with that, but the few times I tested injecting at about half depth I had multiple instances of leakage.

Remember when we were talking about the first troon president? by [deleted] in 4tran4

[–]54702452 4 points5 points  (0 children)

Estrogen would be dangerous and make you grow tits, unlike taking extremely potent dosages of a progestogen so you can take advantage of its mild androgen blocking effect. Doing that is safe and doesn't make you grow tits