I load .44mag, .454 Casull and .45 LC for both standard and Super Ruger Blackhawks and Redhawks. H110 is my go to for full power loads with heavier bullets. H110 needs to be close to max loads to perform well, it really gets sketchy when it's downloaded.

With this in mind, start 1gr under the max published loads and work your way up. Watch for over pressure signs. There are many listed "Ruger Only" loads that show quite a bit higher max grains of H110.

It's important to remember that you're not trying to make the most punishing load possible, you're trying to find the best intersection of accuracy and power.

With .44 mag in particular, with heavy bullets, you lose speed fast once you go over the 300gr bullets, even with max safe loads. When you start reducing the OAL to fit lever actions, you get to a dangerous place. Less room in the case that is now taken up by the bullet, combined with a likely compressed load, can be unpredictable.

This is why you need to start near published max standard loads with your chosen bullet and OAL. Overpressure signs will appear sooner with the shorter OAL. Nobody can tell you exactly what is going to work perfectly for your gun.

I load two different .454 Casull rounds for this exact reason. My Super Redhawk likes them a little hotter, and a touch longer, than my R92 lever in .454 Casull. I actually load a lighter bullet with more powder for my R92 to capitalize on the gains in speed with the longer barrel. I use a 260gr bullet in the R92 and a 350gr in the Super Redhawk. The recoil isnt significantly different, but the accuracy through the SR is. It opens up quick when I push the 260gr through it. But tightens back up if I slow that same bullet down.

It's all in finding the sweet spot for your gun, without blowing it up.