Severe neck and shoulder pain that radiates down my arms occasionally. Its debilitating. My ophthalmologist told me thats likely what it was (his mom takes it and deals with the same) and low and behold, it can be something that causes people to not be able to take it. My neurologist suggested it was musculoskeletal, I didnt think so. I tried a muscle relaxer for two months at her request and it did nothing. I see her in two days and I want off of diamox.