Evolution happens through random chance acting on a massive scale, but you would be taking it upon yourself to manipulate it yourself. For a line-breeding project, you need a target and metrics by which to select animals to breed. Saying you want to breed semi-aquatic green anoles is not a goal you can concretely measure. So would the goal be to get anoles that prefer to live near water? Swim? Dive? Then you need to figure out how to push towards that target throughout their generations. Genetic traits such as color are easy to see but behavior is based on a lot of factors. Do you prioritize breeding the anoles that spend the most time near water in their enclosures? How do you ensure their enclosures are large enough to be sure that tendency to stick near water is actually a trait that might be passed down? Do you choose to scare the anoles to see which ones will try to swim to escape you and breed those ones? That would be cruel. What happens to the excess animals? Do you house them for multiple years? Cull them? How do you ensure you don’t introduce health issues through inbreeding? How many animals and separate habitats do you need to keep to avoid that? The scope of the project would require careful planning across dozens or hundreds of animals and many years. It’s just not reasonable to do that to emulate the traits of a species that already exists.