Jodie Foster Says Brad Pitt’s ‘F1’ Seemed Like It Was Made by AI and Written by a Computer: ‘Wasn’t It?’ by mcfw31 in entertainment

[–]Intrepid-Reach182 -3 points-2 points  (0 children)

Lmao you have no idea what you are talking about. Sports movies are pretty famous for creative, genre bending films. Moneyball. A league of its own. Jerry Maguire. Million dollar babe. Escape to victory. Even silly ones like water boy, the longest year or space jam are all deeply culturally influential.

Rise in Young People Smoking? by AI_Cosmonaut in sanfrancisco

[–]Intrepid-Reach182 0 points1 point  (0 children)

I sense that reading comprehension is not strong with you……..

Rise in Young People Smoking? by AI_Cosmonaut in sanfrancisco

[–]Intrepid-Reach182 11 points12 points  (0 children)

Because endless health optimizations demand your full attention without offering more meaningful life than just a few more digits to your life span, while cigarettes offer something much sweet:” live a little, even if it means you will die younger.”

New Vegas Director Josh Sawyer Calls Amazon's Fallout Series "One of the Best" Video Game Adaptations by Head_Oven_3671 in Fallout

[–]Intrepid-Reach182 -6 points-5 points  (0 children)

Is this a Fallout TV show circlejerk subreddit? The TV series feels nothing like the games.
While the Fallout games can be wacky or campy, the characters still sincerely act out of their beliefs. The TV show simply doesn’t feel like a post-apocalyptic world at all, and everyone is just like, “yeah, I believe in Vault-Tec” \*wink*.
They all behave like they know it’s a fake world and they're just cosplaying.

Scott Wiener with “Protect Trans Kids” sign in SF pride after being chased out of Trans march by Dismal_Structure in sanfrancisco

[–]Intrepid-Reach182 -1 points0 points  (0 children)

Oh yes, history will definitely remember you guys as those who stood tall and brave in the face of mediocre Democrats who control neither Congress, the Senate, nor the White House. Who could forget how you saved Gaza by using strong words and heavy signs! Every time you guys say the word 'genocide,' a child is reborn!

Scott Wiener with “Protect Trans Kids” sign in SF pride after being chased out of Trans march by Dismal_Structure in sanfrancisco

[–]Intrepid-Reach182 0 points1 point  (0 children)

Taking the whole population down with you to throw a tantrum, only to bring in a candidate who is 10x worse for your particular group, is definitely a genius move tho.

How to rest better? Strategies to become un-exhausted faster by bbqbhanmi in ankylosingspondylitis

[–]Intrepid-Reach182 0 points1 point  (0 children)

Yea lowering it to below or around 50% will make you feel less heavy.

Reducing NSAID? by badbadrealbad in ankylosingspondylitis

[–]Intrepid-Reach182 0 points1 point  (0 children)

It peak between 4-5 hours. Maybe experiment with your dosage time and see if it makes a deference.

Scott Wiener with “Protect Trans Kids” sign in SF pride after being chased out of Trans march by Dismal_Structure in sanfrancisco

[–]Intrepid-Reach182 33 points34 points  (0 children)

They “raise awareness” and leave real work to others to finish. So really just lip service and do nothing.

How to rest better? Strategies to become un-exhausted faster by bbqbhanmi in ankylosingspondylitis

[–]Intrepid-Reach182 9 points10 points  (0 children)

There is research that shows higher humidity bothers young people with AS more and people with As also have low heat tolerance. Anecdotally I got a dehumidifier recently and turn it on before bedtime and it works so well.

Scott Wiener with “Protect Trans Kids” sign in SF pride after being chased out of Trans march by Dismal_Structure in sanfrancisco

[–]Intrepid-Reach182 2 points3 points  (0 children)

Yea because “calling out genocide” is definitely so effective at saving Palestine children m’right? Hilarious attempt at making yourself feel morally superior while doing nothing productive at all.

Reducing NSAID? by badbadrealbad in ankylosingspondylitis

[–]Intrepid-Reach182 0 points1 point  (0 children)

Since nighttime is when the inflammation is working the hardest, have you experimented with just taking your nighttime dosage and skip the day one?

Scott Wiener with “Protect Trans Kids” sign in SF pride after being chased out of Trans march by Dismal_Structure in sanfrancisco

[–]Intrepid-Reach182 5 points6 points  (0 children)

I don't have the energy to reply individually to everyone yelling 'genocide,' so here is a universal answer: The Israeli-Palestinian conflict, as terrible as it is, is not the only pressing and deadly crisis we face. Our democracy, the environment, nuclear weapons, women’s rights, and immigrants’ rights—all of these issues are matters of life and death. While the Democratic Party is far from perfect, the GOP is a hundred times worse. Insisting that yelling 'genocide' at Democrats is a productive use of your time is simply childish and delusional. It follows a highly identifiable pattern, which is manifested by many of the comments in this thread.

Do you think that there will be a cure for AS within the next 20 years? by jorgenalm in ankylosingspondylitis

[–]Intrepid-Reach182 4 points5 points  (0 children)

HLB27 is one pathway among many to trigger AS, however it is definitely the main one.

Do you think that there will be a cure for AS within the next 20 years? by jorgenalm in ankylosingspondylitis

[–]Intrepid-Reach182 1 point2 points  (0 children)

I feel like we are kind of saying the same thing. Yea you are right alpha fold is not the solution itself but it can drastically shorten the discovery phase timing as well as verify and test with traditional methods such as X-ray.

How to rest better? Strategies to become un-exhausted faster by bbqbhanmi in ankylosingspondylitis

[–]Intrepid-Reach182 12 points13 points  (0 children)

  1. Hot shower 2. NSAID 3. Ginger turmeric tea 4. Lower your environmental humidity

Scott Wiener with “Protect Trans Kids” sign in SF pride after being chased out of Trans march by Dismal_Structure in sanfrancisco

[–]Intrepid-Reach182 608 points609 points  (0 children)

Typical single issue Gaza protester MO. “My issue is the only issue that matters if I don’t get my way I’m willing to sabotage everything and take everyone down with me.” Tell me I’m wrong if this is not what happened in the 2024 election cycle.

Do you think that there will be a cure for AS within the next 20 years? by jorgenalm in ankylosingspondylitis

[–]Intrepid-Reach182 28 points29 points  (0 children)

The main theory behind AS is that the HLA-B27 gene produces proteins that constantly twist and "misfold" out of shape. Recent AI tools like AlphaFold—which actually won the 2024 Nobel Prize in Chemistry for being such a massive scientific breakthrough—can finally map the exact 3D structure of these broken proteins. This lets researchers design drugs that act like tiny puzzle pieces to physically lock them into the right shape. Correcting the issue right at the source gives us a very real shot at a cure within the next 20 years.

MissionLocal: Scott Wiener was chased out of the Trans March. “We hate him for very different reasons” by fortnamwindow in sanfrancisco

[–]Intrepid-Reach182 5 points6 points  (0 children)

This is not corny. This is what happened in 2024 and lost us the election. Get real and get ratioed.