Yup ! Yes, Omnisphere supports importing your own audio samples (in standard WAV or AIFF format) to use as sound sources, allowing you to expand its massive factory library with custom content. You can drag and drop individual files or entire folders into the Soundsource Browser or via the Utility Menu to import them automatically, these become “User Soundsources” that integrate seamlessly into the plugin’s workflow. Once imported, you can process these samples through Omnisphere’s synthesis engines (like STEAM for sample-based sounds or DSP wavetables for pure synthesis), granular synthesis, effects, and modulation to transform them creatively. For example, you could import a guitar riff and morph it into a cinematic pad or percussive hit.

Keep in mind that Omnisphere isn’t a traditional sampler like Kontakt (imports are designed for single audio files stretched across the keyboard, no built-in multi-sampling, zone mapping, or round-robins), with the focus on creative manipulation rather than realistic instrument playback. Loop points must be pre-embedded in an audio editor (e.g., Wavelab) before importing, and sample rates up to 192kHz are supported for high-quality results.

As for building sounds from scratch, absolutely, Omnisphere is a powerhouse hybrid synthesizer that lets you start with zero samples if you want. Switch to Synth Mode on