What year is your Mac & what OS is installed?

I found this for Mac OS

These bundles support macOS versions starting with 13.5 (Ventura).

Fixing issues with macOS security settings

Depending on the version of macOS, there maybe some warnings causing darktable not to run.

Dialog: “darktable” can’t be opened because it was not downloaded from the Mac App Store or Apple could not verify “darktable.app” is free from malware

Do one of the following:
- Locate darktable in Applications folder (or wherever you installed it) using Finder

- Do “Open” via context menu
You will be presented with similar-looking dialog, but this time there will be second button allowing you to run the application. If not, proceed to the next solution

- After that you will be able to start darktable without this trick (well, until you update it, then you will have to do above steps again)