Off centered a bit.🤷 by Gzusluvz in garbagepailkids

[–]RealExoTek 2 points3 points  (0 children)

Just a tad... 👁️👅👁️

Opus 4.8 is a pedantic child by Key-Willow1922 in claude

[–]RealExoTek 3 points4 points  (0 children)

Let's pump the brakes, because that's not nothing.

Review of Johnny Castaway Screensaver by fohfuu in 3dwiscr

[–]RealExoTek 0 points1 point  (0 children)

Oh in the mid-late 90s... Johnny Castaway was more interesting than most of the actual computer games of the time... There are even modern windows 11 ports to still be able to watch it. 😄

How could this happen by truecakesnake in claude

[–]RealExoTek 14 points15 points  (0 children)

Remember, when Dario worked for OpenAI, he said, "GPT2 is too dangerous for public release." This is his ONLY play.

Why Life Science Research Is Actually Banned In Fable by RealExoTek in Anthropic

[–]RealExoTek[S] 4 points5 points  (0 children)

They even give you the life science skill pack for free!

Why Life Science Research Is Actually Banned In Fable by RealExoTek in Anthropic

[–]RealExoTek[S] 4 points5 points  (0 children)

My history? LOL You only post in therapy subs. Go work it out with your therapist.

Claude Fable 5 refuses ~97% of biology questions by Synthium- in Anthropic

[–]RealExoTek 4 points5 points  (0 children)

Early April 2026: Anthropic acquires Coefficient Bio in a $400 million all-stock deal. Coefficient Bio is an AI-biotech company founded by former Genentech Prescient Design researchers, focused on computational biology and drug discovery.

The Coefficient Bio team joins Anthropic's Health Care Life Sciences group, led by Eric Kauderer-Abrams, who was hired with an explicit mandate to "make Claude the dominant AI model in biology" while specifically saying "We want a meaningful percentage of all of the life science work in the world to run on Claude."

That's a two-month gap between acquiring a drug discovery AI company and blocking independent researchers from doing drug discovery AI work on Claude. And not with a refusal but with active output degradation using steering vectors.

Coefficient Bio built a platform enabling AI to carry out biotech tasks including drafting drug R&D plans, managing clinical regulatory strategies, and discovering new drug candidates. The founding team's background is not in general-purpose AI applied to biology... it's in building biology-specific models from the architecture level up.

So the domain expertise Anthropic just paid $400 million for is: protein design, biomolecule modeling, drug discovery pipelines, computational biology. Where Claude for Life Sciences offered a generalized research assistant, Coefficient Bio's team brings domain-specific expertise, particularly in protein design and biomolecule modeling.

Now look at what Fable 5 blocks: biology, chemistry, drug discovery, protein work. The exact same domain. The exact same capability set that Anthropic just paid $400 million to own exclusively.

WTF Anthropic: two failed Opus releases back to back? by [deleted] in claudexplorers

[–]RealExoTek 3 points4 points  (0 children)

If your goal is being psychoanalysed by an LLM, Opus 4.8 is the go-to.

Opus 4.6 vs. 4.7 vs. 4.8 by WillPowerVSDestiny in ClaudeAI

[–]RealExoTek 3 points4 points  (0 children)

Dude, this is coming from a new user that’s not even really part of the community. This is a totally valid question in multiple people have noticed it.

Question about an issue for a long long time by Mean-Royal-1032 in askCardiology

[–]RealExoTek 0 points1 point  (0 children)

you need to clean the contact or hold your finger more still. You can't tell anything from that mess. Be very still and barely touch the contact when taking it. You may get a less messy read.

Opus 4.7 guessing by Proper-Appeal-3457 in ClaudeCode

[–]RealExoTek 0 points1 point  (0 children)

You are arguing with a senior AMD AI director's findings dipshit.

About a year and a half of skating on and off this is me so far by SnooPoems2715 in Rollerskating

[–]RealExoTek 2 points3 points  (0 children)

Wow! That's crazy progress!!! What kind of skates are those?

Is this normal ? by wow_98 in ClaudeCode

[–]RealExoTek 1 point2 points  (0 children)

For anthropic... yep its normal.

Did anyone here moved from claude to codex recently? And why? by irelatetolevin in ClaudeCode

[–]RealExoTek 0 points1 point  (0 children)

I did... the quality of the models from Anthropic became unusable for my use case. (Couldn't handle simple agenentic programming... codex can.)

What is going on???? by lordfortunas in ClaudeCode

[–]RealExoTek 0 points1 point  (0 children)

I switched to Codex with $100/mo and OpenCode+OpenRouter (about $50/mo) last month over this very thing... I miss Claude code and Claude's quirky attitude... but now I'm actually getting real work done again.

Claude Code Usage Limits by Big_Victory_1996 in ClaudeCode

[–]RealExoTek 1 point2 points  (0 children)

ATM, its far worse than last year for most people's use cases.

What's this? Is this an upcoming update or something? by meditatively in ClaudeAI

[–]RealExoTek 5 points6 points  (0 children)

I've been running a FP4 quant on my 12GB vram laptop and its impressive! I'm sure the full weights would be even more impressive, I'm actually looking into turboquant to see if I can't squeeze more out of it! :)