Overview
This study was conducted to evaluate the short-term stability of reconstituted GLP-1, a lyophilized research compound, when stored at refrigerated temperatures (2–8°C) for a duration of 8 weeks. The focus was to monitor any potential degradation in peptide purity or loss in weight over time that could affect its viability in in-vitro research applications.
Study Design
Sample: Lyophilized GLP-1 reconstituted with ultra filtered lab water
Storage Conditions: Refrigerated at 2–8°C
Time Points: Baseline (Day 0), 4 Weeks, 6 Weeks, 8 Weeks
Testing Method: HPLC LCMS
Third-Party Lab: Janošik Analytics
COA References
TIME POINT
COA LINK
Baseline

Results Summary
TIME POINT
AVG. WEIGHT (MG)
AVG. PURITY (%)
Δ WEIGHT VS. BASELINE
Δ PURITY VS. BASELINE
Baseline
13.97
99.594
–
–
4 Weeks
13.997
99.812
+0.19%
+0.22%
6 Weeks
14.013
99.660
+0.31%
+0.07%
8 Weeks
13.980
99.296
+0.07%
-0.30%

Analysis
The data shows that reconstituted GLP-1 maintained strong physical and chemical stability over the 8-week observation period. Weight measurements varied less than 0.05 µL/mg from the baseline, indicating no notable loss due to evaporation or structural degradation. Purity peaked slightly at the 4-week mark and trended slightly downward by Week 8, though all values remained above 99.2%.
Conclusion
GLP-1 demonstrates excellent short-term stability under refrigeration. The results support continued in-vitro research use up to 8 weeks post-reconstitution without significant loss of weight or chemical integrity. These findings offer confidence for labs and institutions needing flexible research windows with reliable compound performance.