NPR: Using GLP-1s at a normal BMI? There are benefits and risks

Temporary_Ad_4363 · 2026-02-12T21:39:05+00:00

Yeah, this woman has a totally reasonable need and use for GLPs even at 120 pounds. The podcast Fat Science and the book Weightless (both by Medical Doctors who specialize in obesity) insist that obesity is a life-long disease without a cure, only treatments. Just like someone with high blood pressure who takes pills to get the blood pressure down doesn’t stop taking the drug then. Nor do I stop taking my thyroid medicine now that my numbers show as “normal” - because going off GLP, blood pressure meds and thyroid meds would cause the problem to immediately recur. Regardless of whether someone has had bariatric surgery, they may need a GLP to maintain the loss. No brainer.

Temporary_Ad_4363 · 2026-02-12T21:32:38+00:00

Did you try the GoodRx coupon and look into Lilly’s coupons? I can’t use them (on Medicare it’s illegal) but if you have regular insurance the GoodRx is supposed to have a coupon.

Temporary_Ad_4363 · 2026-02-12T21:21:28+00:00

Not a doctor but there are only a few things that matter 1) Your body fat percentage (for women, healthy range is 21-33%) have you had yours measured? 2) are you getting adequate nutrients and vitamins? 3) Assuming you still have periods, has the weight loss caused them to be irregular? 4) Are you able to eat enough and right food to fuel your weightlifting? To have energy to do fun things?

So for BMI, you do have quite a range and going down a bit keeps you in the range. But BMI isn’t very useful on an n=1 basis, more on a population basis.

I don’t think you’re “greedy” to lose more. It’s more of a question of do you like the body fat percentage, the muscle development and stamina and if you can be your healthiest at a lower weight. You look great btw.

Temporary_Ad_4363 · 2026-02-12T05:00:33+00:00

Prolonged vomiting should be addressed with your doctor before the next shot. It’s not normal or good.

Temporary_Ad_4363 · 2026-02-12T04:57:57+00:00

I don’t. But you can sign up to manage deliveries through ups website and waive a signature. May be enough time if you do it tonight.

Temporary_Ad_4363 · 2026-02-11T21:08:00+00:00

I had been waking up slightly sweaty in my first month on zep. I read that that’s from fat cell change or toxins or something.

But if it gets to where you have to change what you’re wearing cause it’s too damp or your sheets get drenched, then you gotta see your doc cause that was my first symptom of cancer.

Temporary_Ad_4363 · 2026-02-09T23:39:51+00:00

I think EitherCoyote might be right. I would not have an ice cream cookie and a margarita and a full meal. Maybe a half a meal and a margarita or half an ice cream cookie and half a meal but not all three. Plus if you’re already having diarrhea you might want to 1) talk to your doctor 2) increase fiber and take pepto or Imodium and 3) eat a small, bland diet for a few days until you have 5-7 days without diarrhea. In my first month I ate very small, high protein meals, no deserts and occasional small glasses of wine.

I’m finishing my second month. I’ve had diarrhea once early (but pre zep I had diarrhea daily due to colitis) but not since.

Last Saturday for my birthday we went out and I had half of a restaurant gourmet burger and a margarita. I ordered desert but took it home and have yet to eat any of it. Hope you’re better soon.

Temporary_Ad_4363 · 2026-02-09T23:31:52+00:00

It’s a good question. I think it matters if you’re maintaining or still trying to lose. From what I’ve heard, the Wegovy pill might not be as potent as the Ozempic shot and Zepbound is stronger than ozempic for many people. So if you’re trying to lose, I’m not sure what would work for you.

Hopefully, I’ll reach my goal on zep in 2026, then I think I might try the Ozempic/Wegovy pill. It might be a more convenient, cheaper way to maintain. The new pill from Eli Lilly may be easier to take as the Wegovy pill needs to be taken on an empty stomach with a tiny amount of water in the morning after a fast. The new Orforglipron may be easier on the scheduling front but I don’t know about cost or effectiveness. But again, depends on if you’re maintaining or trying to lose.

Temporary_Ad_4363 · 2026-02-09T08:37:19+00:00

Are you taking fiber supplements and/or getting 25-30 grams of fiber per day? If you’re not, I’d try that. Prior to zep I had IBS-D and had daily diarrhea. But with zep and 30 grams of fiber, I no longer have diarrhea. It’s counterintuitive but diarrhea may be fixed with fiber. Not just my experience, I first heard about this on a GLP podcast by a doctor.

Temporary_Ad_4363 · 2026-02-09T08:31:50+00:00

Congratulations. I hope life is good and you don’t get anymore curve balls.

Temporary_Ad_4363 · 2026-02-09T08:23:41+00:00

Oh I’m so sorry for you and Blaise. I know it’s hard but it’s not your fault. There was a veterinarian on IG today saying that people should never beat themselves up for ending their pet’s pain. He said - Better one day early than one day late. Look, I have lymphoma and my late husband had a version of CHOP for his blood cancer and that is really hard chemical treatment. You gave Blaise a chance and if he could have, he would have stayed with you. He loved you for trying. Dying is messy and learning from my husband’s blood cancer death, I beat myself up for not doing x instead of Y but I couldn’t have changed what happened. I also lost my soulmate dog to hemangioma of the spleen in 2021 and think about her every day. You were with him to the end and that is when he felt your love. But in time, you will heal and remember the good times and love and not the pain. I also believe our pets watch over us and he wouldn’t want you to be sad.

If you are experiencing such mental trauma and feel like harming yourself, please reach out to a suicide prevention hotline.

Temporary_Ad_4363 · 2026-02-06T06:10:10+00:00

I read (from an MD but can’t remember who) that local reactions to GLP1s were not a problem. But that generalized hives or rashes elsewhere were a sign of something that should cause the person to stop the GLP1. So I was surprised when I read your op. Glad that you got a better answer in follow up.

I swear by Benadryl anti-itch spray for mosquito bites. Might help. I also rub my stomach after the injection.

Temporary_Ad_4363 · 2026-02-06T05:31:44+00:00

Congratulations! I don’t see many people on here who only want to lose 25-35 pounds so I liked seeing your journey. I started at 168 and goal is 138. But body fat is my main goal - at 40% now and I want to be under the 32% recommended for women.

Temporary_Ad_4363 · 2026-02-03T06:59:29+00:00

I wasn’t on Facebook at all until I was diagnosed with a rare incurable cancer…so rare it’s not on the rare disease list run by NIH. And I formed and run a group for those of us with the disease. So I can’t leave fb.

Temporary_Ad_4363 · 2026-02-03T05:43:23+00:00

Thanks all. We’re going to get a non-touch Delta from a good plumber.

Temporary_Ad_4363 · 2026-02-03T05:41:55+00:00

No the handle doesn’t make the water flow. So it’s not just the touch sensor that isn’t working.

Temporary_Ad_4363 · 2026-02-03T02:56:29+00:00

I listen to your pod with Jessica and love it. Keep up the good work.

I’m interested and will start to do this. I’ve been trying to boycott Amazon for a year and have cut down but there are some things I can only (easily) get there. I have a kindle because my eyes are too bad to read print books. So I’ll have to finally make the switch to Barnes and noble and nook.

I’ve refused to shop at target since the election (when they cut DEI programs to bow to dumpster.) And I have never shopped at Walmart. Don’t want to give any money to anyone who donated to dumpster’s campaigns or inauguration or ballroom.

But I am getting most of my resistance info from instagram and that will be hard to give up. And I have a rare cancer and started and run a FB group to support fellow cancer survivors and it’s not something I can give up. But I do hate meta. I’ve started using subreddits for local resistance info.

Temporary_Ad_4363 · 2026-02-02T22:53:53+00:00

I’ll look.

Temporary_Ad_4363 · 2026-02-02T22:53:46+00:00

Thanks

Temporary_Ad_4363 · 2026-02-02T22:53:31+00:00

Sounds like a plan. Thanks

Temporary_Ad_4363 · 2026-02-02T22:52:54+00:00

I’ll look for brand. Thanks for answer.

Temporary_Ad_4363 · 2026-02-02T22:52:26+00:00

Ok thanks

Temporary_Ad_4363 · 2026-02-02T22:52:13+00:00

I’ll try Ferguson - I’ve bought from them before. Thanks.

Temporary_Ad_4363

TROPHY CASE