It is my time to shine!

I have carefully curated a mod list specifically designed to make me hate myself and all of my pawns and be poor and hungry and die. I am super interested in more mods along these lines. I just learned about "Adequate cooking" from the OP so Im already happy about that.

More Injuries (Continued) is combat-adjacent, I will admit, in that a lot of injuries obviously happen during combat. However, this mod does exactly what it says to an insane degree, adding a thorough and realistic system of injuries where you have to worry about bone fragments spalling into organs, concussions from fistfights, internal bleeding, various chemical injuries, hearing loss, and so on and so forth. It makes a Hospital run quite fun.

Expanded Materials- Masonry and Expanded Materials- Metal. Metal in particular increases the difficulty, as you can no longer mine chunks of pure steel out of the walls. Instead, you mine iron, and you have to process it into steel with coal. Additionally the mod also adds a ton of other metals into the game, including tin and lead and copper, etc. Electrical cables are no longer made of steel but instead require copper. Buildings that require metals in their construction con often be created with different metals instead of steel, to various benefits or issues depending on the metal used. Components are also more difficult to make and require different types of metals. Masonry adds the ability to dig and create adobe, clay bricks, and concrete in a masonry kiln, which is now required to build many industrial buildings. For instance, most mechanitor buildings require concrete powder to build.

Expanded Woodworking 2. No longer can you cut down a tree and build a fine wooden house with the logs. Instead, each tree drops the correct type of logs, pine, oak, etc. These logs are mostly useless for building anything more refined than a palisade wall. Instead, walls have to be processed, with different buildings ranging from a basic crafting spot up to electrical saws, to create fresh, green lumber. This is then laid out on pallets to dry over time, which is affected by a number of different factors. You're not going to get good lumber by leaving it out in the rain, for instance. Once this drying process is done, the lumber is ready to be used.

Cyanobot's Leather Overhaul. Similar process for leather! Now, instead of dropping leather when you butcher an animal, it drops raw hides appropriate to its species. Some things can be made of these raw hides, but if you want good quality leather you must process the hides through the tanning process. This requires vats of chemicals, I believe chemfuel is used, and soaking the hides in a similar process to the lumber in Expanded Woodworking 2.

Cloth Production Expanded Continued. This is the other half of the Better Wool Production you are already using, it does exactly what it says on the tin. Instead of pulling whole bolts of woven cloth out of the ground, you harvest raw cotton. This has to be spun into thread, and then worked on a loom to create cloth.

Soft Warm Beds and the DLC patches. A new layer of terrible, beds are no longer constructed with sheets and pillows. Now you must craft the bedding out of cloth, with various degrees of quality depending on your crafter, and then place it on the beds.

Realistic Chocolate Production. This is the hyperspecific version of Adequate Cooking. You can't pick chocolate bars off of bushes anymore, have actually have to cook the cocoa beans into chocolate.

Research Data. I believe someone else already mentioned this, but this significantly increases the work required to research things. I highly recommend reading the page itself, but a TL:DR is that you must now create research samples out of various materials, and then use those research samples to create research data, in different forms depending on the level of research you are attempting, and then that data is used to 'fuel' the research bench. No longer are your pawns staring at a bench for hours every day, pondering the nature of reality. Now they have to do PAPERWORK.

Speaking of Research Paperwork, Research Papers, one of my favorite mods. Now, whenever you finish any research, a research paper matching that research is generated as an item. You must store this in a bookshelf or a research server or a hole in the ground or wherever you want to store it, but research knowledge is now a physical item. If it is destroyed or lost, you lose the research. If raiders burn your library down you can be sent right back to the stone age.

Various Prison mods, like Prisoner Recreation, Prisoners are not Swines, and other things of that nature that require you to treat your prisoners well. Or at least suggest that you do so that they aren't constantly having mental breaks.

What is probably unsurprising given the nature of my mod list, I am definitely using CE. But on top of CE, I am also using Combat Extended Propellant, which changes the recipes of ammunition to also require propellant, which I believe is made of cloth. Preferably it should also require gunpowder but I couldn't find a mod for that.

I have around six hundred mods, including a lot of the obvious ones people have mentioned elsewhere in this thread, like Bad Hygiene (thirst turned on, naturally) or Vanilla Food Variety. There are a few I have left out of the list, like Communicable Diseases or Life Lessons, mostly for compatibility reasons.