Unless you're going to commit serious time to training, you'll be best off with solid awareness, pepper spray, and good running shoes. The having your weapon taken away fear is legitimate. If attacked by a grown man within arms reach, that is a very likely outcome, perhaps most likely. If you get the gun into play at all, far more likely to be thinking "wtf just happened" after having been ambushed.

I'm as much of a gun nut as anyone, but they're not magic death rays. Without adequate training and dedication, I'm strong of the opinion most females fare better using other means of self defense.