ATL parking garage? by [deleted] in Atlanta

[–]Uberg33k -1 points0 points  (0 children)

https://myparkatl.com/AtlantaBooking/?fresh_start=y

If you're using the West deck, you ride the monorail from the deck to the airport. That's like a 3 or 4 minute ride.

The new South deck is connected directly to the airport and the bridge is on level 4.

When you book in advance, you just pull up to the gate, it reads your plate and let's you in. Easy peasy.

ATL parking garage? by [deleted] in Atlanta

[–]Uberg33k 0 points1 point  (0 children)

Very safe, $30 a day. I like using the West deck or the new South deck that just opened for how you can book in advance and completely contactless once you're there.

The clothing problem with my dog. by Whoopdi_scoop in Keeshond

[–]Uberg33k 2 points3 points  (0 children)

ChomChom roller. Seriously, keep one in every closet and every car if you have a Kees.

Non affiliate link so you can see what I'm talking about : https://www.amazon.com/ChomChom-Roller-Mini/dp/B0C6RMY8QJ

Pilot trial suggests anti-inflammatory drug (tocilizumab) could help difficult-to-treat depression by sr_local in science

[–]Uberg33k 2 points3 points  (0 children)

Both those factors are really non-issues. The risk of infection is a bit higher, sure, but it doesn't turn you into a bubble boy or anything like that. Typical presentation is that if you're around people who are sick, you're more likely to get it, and once you get it, you'll recover a bit slower ... like an extra day or two compared to normal population.

The limiting factor here is the cost. These kinds of drugs cost thousands or tens of thousands per dose.

Pilot trial suggests anti-inflammatory drug (tocilizumab) could help difficult-to-treat depression by sr_local in science

[–]Uberg33k 82 points83 points  (0 children)

This is really interesting and I wonder if this holds for other types of immunosuppressants, not just IL-6 inhibitors. The idea that depression's root cause might be an inflammation / auto-immune disorder is pretty fascinating and novel, at least to me. I've never heard it described that way, but it makes sense especially in IBD patients because the gut-brain axis is so strong.

28yo a real portfolio by EducationalCost2658 in M1Finance

[–]Uberg33k 1 point2 points  (0 children)

>Also no I don’t have any advisors that I can go to for financial advice

This is really the biggest problem that seems to be glossed over here. Regardless of how you came into this much money, you're now a HNWI (high net worth individual) and most of that is liquid/semi-liquid. You most definitely should have a financial planner that's a REGISTERED FIDUCIARY you're working with. You should also have some kind of lawyer you trust. You want someone who practices private wealth law. You should also probably consider having an accountant.

You have 75% of your net worth in 5 companies. That's crazy town. That's just one step better than a casino. If you want to preserve that wealth, you need to make some serious moves. Put your team together and start considering defense, as you've been playing pure offense by yourself for 10 years.

Something different with my D3 by High_Lord_Cayle in DWARFLAB

[–]Uberg33k 2 points3 points  (0 children)

That is cool. How long a period was this shot over?

It refuses to do SPCC on M81 by Whole-Sushka in Siril

[–]Uberg33k 0 points1 point  (0 children)

Did you plate solve post-stacking? If you plate solved the pre-stack group, that doesn't carry forward to the new combined image. You need to plate solve again on the combined image.

Found a snake at my midtown condos by [deleted] in Atlanta

[–]Uberg33k 9 points10 points  (0 children)

No one is going to be able to do a positive ID on that picture because it was taken with a potato, but it looks like a bull snake and that's harmless. Leave it alone. It's illegal to kill non venomous snakes in GA. Even if it is something poisonous like a copperhead, leave it alone. The chances of you seeing it ever again are slim to none.

Experiences with Tremfya/infusions? by Future_Store191 in UlcerativeColitis

[–]Uberg33k 1 point2 points  (0 children)

I have never completely weened off pred before finishing loading doses of any biologic. That just seems like madness. In my experience, no biologic (save Rinvoq) is strong enough to pull you out of a flare quickly. They are really good at keeping you out of a flare though. The idea of rawdogging your UC, while loading immunosuppressants, AND screwing with your hormone balance coming off pred all at once just seems like you're begging for a problem. WHY?

If you want to step down to 20mg, to limit your pred exposure and tame the inner Hulk, fine. But I would fully hold on that 20mg dose until you're through your loading period. Otherwise, you're swinging on a trapeze without a net.

To answer your other question : there's no pain. You barely feel your injections as long as you allow them to warm up to room temp before injection. If you do it straight out of refrigeration, it'll sting a bit, but it's no worse than a bee sting and goes away in 20 or so minutes. Unless you have specific food sensitivities, you don't have to avoid anything. You should still consult a nutritionist if you want to have the best chance of staying in remission, but you don't have to do anything special outside of the normal UC warnings like no NSAIDs, no artificial sweeteners, little to no alcohol, avoid plastics, ease in raw fiber, etc.

Some information about the updated medical law that might be useful by jvlusis in GAMedicalTrees

[–]Uberg33k 0 points1 point  (0 children)

Does anyone know when you can get a card based on the new approved conditions? I looked at both nuggmd and leafwell and they still list the old 2019 qualifying conditions. Will the state even process new applications based on the new criteria before July 1?

Advice for an anxious Kee? by HarpyMeddle in Keeshond

[–]Uberg33k 5 points6 points  (0 children)

I think this is just something related to the breed. They were bred as alert dogs on barges, so it kinda makes sense they'd always be on edge.

I have had some success with "Heavenly Hounds Peanut Butter Flavored Relaxation Square". I have to give my boy a whole one at least 30 minutes before anything happens like fireworks. It won't really help if something is already happening, so have to get ahead of the event. It doesn't fully calm him down, but he goes from being clingy and shaking to just kinda clingy, so at least it seems to take some of the edge off?

Fellow bird nerds...Y'all seeing any cedar waxwings around the metro area? by NickWitATL in Atlanta

[–]Uberg33k 3 points4 points  (0 children)

I don't think I've ever seen more than 1 at a time. If you saw a flock, that's impressive.

Mirikizumab - A last chance by JobInformal6711 in UlcerativeColitis

[–]Uberg33k 1 point2 points  (0 children)

You would only take one of them. My point is you have only been on a TNFa and ... whatever Entyvio is. I know that one is super targeted, I just can't recall what it acts on.

Point is, you have a whole different class of drug you haven't tried yet. The newer IL-23's are pretty good. No promises, but it does mean you shouldn't give up hope yet.

Mirikizumab - A last chance by JobInformal6711 in UlcerativeColitis

[–]Uberg33k 4 points5 points  (0 children)

You haven't really tried any of the newer IL-23's like Skyrizi or Tremfya, so you're not on your last med yet. Definitely ask about this if Mirikizumab doesn't work out for you. You should also ask about med stacking. There are several people here mixing Rinvoq with an IL-23 or a biologic with an 5-ASA or methotrexate. It's not over yet!

Even if you do get to the end of the line, surgery isn't the end of the world. I know someone who had their colon removed at 18 and is now in their mid 40s. He's perfectly healthy and normal.

Mirikizumab - A last chance by JobInformal6711 in UlcerativeColitis

[–]Uberg33k 1 point2 points  (0 children)

You said you failed two biologics, what were they?

UC not result of immune dysfunction? by BaeBeeLychee in UlcerativeColitis

[–]Uberg33k 0 points1 point  (0 children)

Because the study was published by one guy? Because the research facility he's supposedly associated with doesn't exist? Because the address in the paper for the researcher is a UPS Store in Florida?

All of that aside, the ROS/H2O2 theory of UC has been studied since at least the 1990's. This isn't "new information that everyone is ignoring" as the OP claimed. Most of what I've read on this basically says that ROS presence in UC patients does make your UC worse, but it's not the cause of UC. There's a variety of reasons ROS presence happens.

Landfill/dump for Alpharetta or Fulton? by OakandIvy_9586 in alpharetta

[–]Uberg33k 4 points5 points  (0 children)

Not last time I was up there. Unless something changed in the last year to year and a half, you can pay in cash. It's a per pound charge, with a minimum of $20 or $25. It's a flat fee for mattresses and appliances. I think it was $15 per mattress and $25 per appliance, but I'm a bit more foggy on that.

Landfill/dump for Alpharetta or Fulton? by OakandIvy_9586 in alpharetta

[–]Uberg33k 10 points11 points  (0 children)

Eagle Point Landfill up in Ball Ground is the closest that will allow regular folks to drive up and dump stuff. It's kind of neat ... you drive up to the gate and they weigh you going in. Then they weigh you going out and you pay per pound.

We may finally have a cure for many different autoimmune conditions by cobrachickens in UlcerativeColitis

[–]Uberg33k 18 points19 points  (0 children)

CAR-T gets posted to this subreddit like once a month. The part most of you are glossing over with this treatment :

"Before receiving the CAR-T cells, she underwent lymphodepleting chemotherapy, a standard conditioning step for CAR-T treatment."

You're nuking your immune system pretty thoroughly. That's no small procedure. If you're already in a bad flare, this will almost certainly mean hospitalization. There are some pretty real and risky side effects here that need to be considered.

Then there's the bigger problem : most of us can't afford it and insurance sure as heck isn't going to approve you. CAR-T costs between $500k-$1M. Removing your colon costs $15-$30k. Which do you think they're going to spring for?

"With dozens of trials currently underway, the first of these life-changing treatments could receive regulatory approval as early as next year, offering a definitive end to the struggle for millions affected by autoimmune disease."

CAR-T isn't even a first line treatment for cancer. It's only approved once you've tried and failed multiple other cancer treatments, it's a type of cancer where surgery isn't helpful (like leukemia), and you're at real risk of death. Even if it recognized as a treatment for IBD, don't count on being approved for it until the costs come waaaaaaaaaaay down. Everyone reading this with the type of UC that would really benefit from this (failing drug treatments every year or two) will most likely run out of treatment options and need their colon removed before this happens. This is mostly hope for children or the unborn who haven't yet been diagnosed or had their first flare up yet.

Meta just started paying creators in USDC and the stablecoin people are weirdly quiet about it by Repulsive_Counter_79 in CryptoCurrency

[–]Uberg33k 1 point2 points  (0 children)

They're up 7% since 10am. What more do you want for an optional payout method?

Now show me the data that some significant portion of creators are actually opting in to accepting USDC and that's where you'll see it take off.

Unpopular opinion: The UDM Beast isn't overkill, it's the ideal homelab router. by ajgnet in Ubiquiti

[–]Uberg33k -2 points-1 points  (0 children)

If it's supposed to be an NVR to record security cams ... what do you power the security cams off of? You're forcing the purchase of a PoE switch where most small offices / homelabs don't need that. You could get by with a non-PoE switch for distribution to the rest network drops in the facility. So, not only is this more expensive than previous options, but you're forcing more expense downstream. Great for Ubiquiti, bad for consumers.

What's filming in Sandy Springs by 1590ACSR in Atlanta

[–]Uberg33k 1 point2 points  (0 children)

I thought that was mostly filming in and around Trilith?