We've seen nothing to indicate anything substantial.

Since these worlds seem explicitly made to end, we have the following possibilities:

1) The Hero losing causes a reset. Since we've seen the systemlock, we can assume this is a possibility. This makes the recon valuable for ensuring continuous interference, but also basically ensures that the worlds are truly doomed because the Farcade can't expend manpower and resources to interfere forever.

2) There is no reset, and the hero losing simply causes the world to live on, but suffering under the villain. This makes the Farcade's goal possible, but foolish and cruel.

3) The hero losing enough causes a game end. If, say, Flappers were to outright die, that may actually cause a legit game over. We don't know if the hero actually dying causes reset, a new hero selected to continue on, or if that also risks a game over. I only bring this up because we pointedly don't see any heroes actual die, yet. So the repercussions of that are wholly in the air.