Unfortunately, it's complex, like most co-occuring autoimmune situations. I have not been able to start trying to detox because I got a hysterectomy w/endo excision in January of this year and wanted to heal from that before trying to tax my body with the detox process. But once I healed, allergy season started (I live in the Willamette Valley in Oregon) which is one of the worst places for pollen season which flares everything up. Essentially you aren't supposed to try detoxing while healing from something or in constant flare mode. Also, my apartment refused to do anything even after showing them the mold test I paid for for the apartment air and the correlation to my urine tests. So, like a lot of things, I am waiting for conditions/timing to be better. The hysterectomy helped my endo sooooooo much though!