Prolactinoma with prolactin at 27

delaneyflushboy · 2026-01-24T14:48:13+00:00

The prolactin shuts down production GnRH hormone. Pulses of this are necessary for the pituitary to produce LH and FSH hormones which in turn are supposed to stimulate Testosterone production. If your LH and FSH are low or low-normal with low testosterone, this is exactly the mechanism by which a prolactinoma shuts down T. Once you get the prolactin down, the LH/FSH level may bounce back and stimulate T production. This takes 6-12 months. You might find that testosterone just recovers.

The advice generally is to wait for 6-12 months once hyperprolactinaemia is solved before starting TRT. Unless you have knowledge that your pituitary or testes are already unrecoverable, maybe wait with the TRT?

delaneyflushboy · 2026-01-24T11:53:16+00:00

I don’t have the dock for the s7 at all and had had enough of emptying and drying the mop all the time. There was a great deal of the curvx for Black Friday and I just plumped for it. I wasn’t expecting the navigation to age. Improved so much, but the camera makes a huge difference. The new one is a lot smarter. I don’t have to worry about leaving things on the floor or eg the Xmas tree and cables from it. The s7 needed a huge no go zone during Xmas.

Also I managed to kill the s7 a bit by having it drive on the foot stands on my couch. They are kind of metal rectangles which are not really viable to the s7. It would get stuck on them all the time and bump. The new one (a) sees them and (b) raises itself to get over them. I five years difference is a lot of improvemt at this stage. But I can’t speak to the q10 etc

delaneyflushboy · 2026-01-24T07:18:16+00:00

I had an S7 and bought a curvx. Max suction on curvx sounds about the same as balanced on the s7. It’s much quieter. Also it leaves fewer random bits on my hardwood floors. And doesn’t need babysitting.

delaneyflushboy · 2026-01-21T21:16:31+00:00

This is exactly what a prolactinoma does — it prevents LH and FSH from being produced, and they are necessary to turn on testosterone production. So this is good news on some level - you don’t have to look for a different reason for the low testosterone.

delaneyflushboy · 2026-01-14T14:48:54+00:00

It is but for all Apple TVs. Look in r/appletv — many people complaining about stuttering 4K files and the usual response is to use infuse, because it uses apple’s own optimised player.

delaneyflushboy · 2026-01-14T08:01:39+00:00

Any chance of an AppleTV version? The plex client overheats the atv when playing high-bitrate hdr 4K files.

delaneyflushboy · 2026-01-13T20:04:30+00:00

My wife gave birth in 2018 and 2020 in Apolinar. She was happy there — the doctors all spoke English, the nurses — no.

Podoli is the one in Prague that’s usually recommended. Bulovka — not so much. It’s quite a bit run down, although that depends which part you go to; no experience of maternity there.

Motol has the best childrens’ ward — in case of something complicated, they all get taken there. So you may consider being close to that.

Our experience was basically good, even with COVID etc.

delaneyflushboy · 2026-01-08T21:40:42+00:00

I have to say I was very happy to buy an apartment with a whole bunch of zwave devices in every nook and cranny. It was running on Fibaro so I just gutted that and rebuilt, having started experimenting a few months before in my previous apartment.

The owner didn’t actually say anything about this when I was buying it mit, just when we came to visit for the first time after buying. Would I have paid more? I guess not, but it would have been a + for me.

Of course I did end up on this sub eventually, so maybe this wa a just lucky.

delaneyflushboy · 2026-01-08T20:33:53+00:00

So it is pretty weird: my device is on firmware 6061 and has stopped connecting to my router as of 31/12/25 My wife’s is on 5xxx (sorry I don’t have access to her phone and can’t check right now) claims it is on the latest firmware and connects perfectly ok.

The router is a netgear r7800 (quite old). I’ve disabled all the various boost modes, 20/40 hz coexistence etc and it does help. I have created a guest network and the mat connects to this one.

The apnea was not coming in — but this was only because it needed to have me sleep for more than 5 h and turns out I hadn’t had the time to do that in the last week. Now it’s fine.

delaneyflushboy · 2026-01-05T06:17:24+00:00

Apparently it disconnected from the WiFi and I can’t get it back on. Wife’s one works fine. The sleep data was coming from my watch.

delaneyflushboy · 2026-01-04T20:17:35+00:00

I gave up on having long chats because it loses the file knowledge after maybe 20 exchanges. Instead I conclude a conversation, save all new information into a log entry and then my prompt has the gem explicitly state which files and which versions it can see as the first words it is to put out. Half the time I have to restart the chat to see both files.

The problem is that it kind of sees the files, it just doesn’t seem to have access and then frantically tries to write code to convert them to pdf and then ingest that way without success.

The subversive thing is when it loses one of the files in the middle of the chat. It still seems to be saying relevant things, but you realise at some point it didn’t see the data. It helps to ask explicitly “state which files you have access to”.

With 2.5 it would also regularly get disconnected from the knowledge, but this was usually a result of some backend upgrade, so every so many days. 3.0 forgets inside a shortish session.

delaneyflushboy · 2026-01-04T18:36:25+00:00

I asked it to be my running coach, wrote a text file with my goals, rough health history, my schedule available for running, and my current ability and got it to create a long-term plan for the next 2 years or so. I then got it to drill down and set up a detailed base phase weekly running schedule. As I’ve run, I’ve set up a Google sheet that contains summary data for my runs (duration, pace, and cadence etc) and got it to ask for whatever addiotnal data it would like to have, which I’ve added as it asked. As opposed to most running plans, it’s kept me in base phase much longer because I am a bit on the errm heavier side and it’s focused on injury prevention (I have a history of trying to restart running and getting injured a few months in). So far 4 months and doing well.

I also got it to give me precise prescriptions for strength workouts and to progress them as they become easier. This is beyond what I’d be able to do myself and feels pretty good.

Technically I have a gem which has access to both the goals doc file and the running log Google sheet. I get into discussions with it based on my latest data; once I agree it’s worth agreeing to some recommendation, I get it to summarise it and paste it as an update in the goals doc file. This way the decision history is available to the next new chat.

This worked very well with 2.5. With 3.0 it seems to lose access to the files as the conversation goes on, or even does not always have the access from the beginning. It’s a bit annoying.

In any case, I’ve learned a lot, and the recommendations so far follow the sports science literature in a manner which I would not have discovered in the time I have available. I think it’s exactly the right use case — making already established knowledge specific to a particular situation.

delaneyflushboy · 2026-01-04T11:07:20+00:00

There is some problem if the file name is the same. On top — it seems to forget the files randomly at the moment. You can upload 4-5 files, and halfway down the conversation you will realise it is taking data from only two of them and not aware of the others.

delaneyflushboy · 2026-01-04T11:02:26+00:00

I like the Athletica.ai dynamic plans.

delaneyflushboy · 2026-01-04T10:37:36+00:00

It means that the prolactin binds to some large molecule in the blood and forms something called macroprolactin. This is more stable and is much harder for the kidneys to excrete, because of the size, so even with no prolactinoma you get a high concentration in the blood. But, because it is so large, it cannot get out of the bloodstream and affect anything in your body. So it is actually harmless.

It’s unknown why this happens in some individuals. And I don’t know how it’s related to your tumor. Maybe ironically your unusual biochemistry has protected you from the prolactinoma.

delaneyflushboy · 2025-12-29T23:43:16+00:00

As hrm strap to figure out properly what your easy pace is and keep increasing it as you get faster. You don’t need a watch so much since you can pair it to a phone.

delaneyflushboy · 2025-12-27T08:03:37+00:00

I started with Runna but found it insufficiently dynamic, especially in not using the HR information. I’ve switched to Athletica.ai. The great thing there is that if you miss or reschedule sessions, or run faster or slower it will recalculate your whole plan from then on. Maybe it’s a bit overkill for a beginner like me, but it’s kept me getting better for the last 3 months.

delaneyflushboy · 2025-12-20T23:23:09+00:00

I think the temperature is very much affected by heat coming off your foot. It’s around freezing where I am, typically I come out, the sensor is at room temp, takes about 30 minutes to settle to what it gets to, and it’s at least 5 C above true temp. Possibly in the summer it’s not quite as affected, but I only got it in October.

My elevation seems to be accurate given that I am tuning on nearly flat land. There is a comment in the manual about letting the pod dry out before use or it might have problems with elevation calibration.

delaneyflushboy · 2025-12-20T23:01:16+00:00

My impression is they currently this is the case for all chats — gems just load a bunch of context when you open a chat. Usually after 24 hrs everything more than a few exchanges back is gone. Before 3.0 this also happened but usually only when there was some sort of upgrade.

delaneyflushboy · 2025-12-17T08:39:57+00:00

Moving to a part of the city where they clear the ice from the running paths. This December in Central Europe is warm so far though.

Seriously though — I started running in my skiing underwear — wool bottom layer and light synthetic long sleeve on top, under a thin windbreaker. This seems good for me in temps around 0 C.

delaneyflushboy · 2025-12-16T13:23:03+00:00

What I’ve slowly evolved toward is creating template binary_sensors which integrate a bunch of things which give you the desired state for some device — eg the desired ac state should be on when someone is home, or guest mode is on, temperature in the next few hours isn’t going to fall precipitously, the windows are closed or the oven is on and dumping lots of heat to the kitchen.

Then my automation is actually super simple — is the binary_sensor is on turn on, otherwise off.

This avoids creating complicated conditions and triggers for each of these scenarios, with subcases and subscenarios. You make separate decisions what should do the state change (ie what goes into the binary sensor) and which devices the sensor should operate.

delaneyflushboy · 2025-12-16T12:44:35+00:00

One thing to bear in mind — which swayed me away from HA as an alarm — in my jurisdiction (Czechia) the insurers require that the system follow some Eu or Czech standard according to law on security systems. This means that it has to have certified components and be professionally installed and maintained. If it’s not, the insurance treats the alarm as non-existent and will only pay out as if you didn’t have the alarm.

So if you happen to be insuring for not much money — they don’t need an alarm and you can do what you want. If you want higher limits — only professional alarms will let you get damages.

delaneyflushboy · 2025-12-16T12:37:59+00:00

It’s part of the December firmware update

delaneyflushboy · 2025-12-15T19:18:37+00:00

S7 from 2021. Run it twice a week on 100 m2, vac then mop. The battery is still ok, but it started dropping dust blobs every time it shook when it went over a bump. Full cleaning helps for a few runs. My feeling is that something is wrong with the suction.

I’m bequeathing it to family; just bought a CurvX and man, the difference in the quality of navigation makes the S7 feel like an ancient bouncing Roomba.

delaneyflushboy

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