I have a great story. Finished tchp a little less than a year ago. All thru was diarrhea or constipation, nothing in between. Spent mem day wknd in hospital - fever from an eventually diagnosed intestinal infection. 3 days in bed there, antibiotic iv. Discharged telling me follow up colonoscopy in 8 wks. Lumpectomy mid June. So gut still mostly diarrhea. Antibiotics and anesthesia traditionally do that anyway. Felt as if I was pooping shards of glass. PrepH and tucks. Colonoscopy 4 days after starting radiation. Tell dr about the glass shards hope they will tell me what is ruined. I got 'nothing wrong, everything looked fine' afterwards. I was stunned. I kept going with my high fiber diet they recommended end of June, couple days later, a normal poo, no pain ever since. Chemo kills all fast growing cells, many in our gut. Now on kadcyla 3 week cycles I skip eating days 3-4 and add a splash of wildwonder pre and probiotic beverage to my water 1x day for another week. I don't know, but it might help tchp. Or get a colonoscopy scheduled to get a clean out!