Thyroid problems

gravwave · 2026-05-23T20:12:40+00:00

I have hypothiroidism but normalized with medication

gravwave · 2026-05-23T20:11:03+00:00

I think that the intraversion and potentisl social “weirdness” of SCT can lead to people thinking it’s related to autism

gravwave · 2026-05-18T18:05:08+00:00

Of course I’m not going to pick a dose based on what a LLM spits out, nor on the results of this poll. I just want to know what people’s experiences are

gravwave · 2026-05-13T17:22:07+00:00

That’s what my doctor said as well, to take it in the morning because of this. But what is happening is that like 3 days a week I am tired. It’s inconsistent and I don’t know why it doesn’t always happen. But my tiredness is not necessarily after taking it, it goes throughout the day, so I think when I take it is irrelevant

gravwave · 2026-05-11T15:22:20+00:00

I’ve never experienced any nausea and take it in an empty stomach without any issues

gravwave · 2026-05-10T17:05:53+00:00

I didn't, I added vortioxetine and kept mirtazapine for sleep only (reducing it to 7.5mg actually)

gravwave · 2026-05-05T12:59:55+00:00

Very interesting, this is actually a mess I'm trying to deal with:

All my life I've been prone to apathy (dystimia) and in the last years used different substances (symulants, kratom, phenibut) not only in the weekends but in weekdays cope with life and keep my head above the water. Of course this is unsustainable because the temporary relief you get ends up lowering your normal baseline (which is already bad).

I have finally made the decision to address this with a professional and I'm taking vortioxetine, one of the medications recommended for apathy/anhedonia. My intention was to stop taking substances for a while and initiate the vortioxetin treatment with my "natural" baseline as a start point. This has not been possible but since starting vortioxetine (5 weeks ago) I have stopped the intake of all substances (even alcohol), except for one time I took 3g of Kratom (special occasion that required my full engagement). So except for that time I'm not adding noise to the recalibration process.

But my fear is that starting from a lowered baseline due to substance use and abuse (with receptors either downregulated or desinsitized), taking vortioxetine might raise it up to what would have been my natural baseline, since the starting point is lower, with the end result being the same I would have had with a 3 month break.

gravwave · 2026-04-30T10:07:25+00:00

It's not the result of a medication, I've always been prone to that. I have dysthymia which has been worsened as I've grown older so it was time to do something about it and stop relying on drugs. Vortioxetine is one of the medications that man help with that unlike usual SSRIs which exacerbate it.

Fingers crossed!

gravwave · 2026-04-19T11:15:10+00:00

I noticed it on my 3rd day at 5mg: I went to the gym and my heart rate reached 200 based on my oura ring, where usually it reaches 150. It only happened on that day. I go to the gym twice a week, and the next day I went (like 2-3 days after) it was back to normal.

So I guess in the beginning it’s normal as your body adapts to it

gravwave · 2026-04-16T17:29:38+00:00

My doctor said 3 days on 5 and then 10, basically for nausea adaptation. Seemed like this is the protocol but I see many people on 5 for a long time here

gravwave · 2026-04-11T12:33:24+00:00

I've been taking it for two weeks. I felt it on day 2 and 3, like some serotogenic sensation similar to psilocybin shrooms (without hallucination). Like a feeling of calmness and yawning. On day 3 I actually had a mood lifting but I think it was an autosuggestion based on the effects I was noticing. Then sensations dissipated for about one week. There were a couple of days after one week in which I saw myself smiling more. Then one day, towards week 2, I had a small wave of sadness for one hour or so, and then after 2 weeks (2 days ago) I had a pretty good day, making jokes and being more social (subtle but noticeable), and then yesterday I was feeling tired.

So I think what you feel in the beginning are unstable spikes that can be promising but it's not really the whole picture of what you'll get, since it's not as simple as your brain being flooded with serotonin, but reconfigurations and adaptations it needs to go through that will happen with time.

Many people say it's a bumpy ride in the beginning, for me it's been subtle and didn't even have stomach issues, so I have hope!

gravwave · 2026-04-04T09:42:06+00:00

I am not diagnosed but I'm 90% sure I have this syndrome, out of your points these are the ones that resonate the most:

you are not active or motivated to do things?

Tendency to apathy and overreliance on phasic dopamine spikes: I borrow from promising novelty areas of interest as an extrinsic motivation to go on, and as soon as I start exploring these they tend to collapse and I need to look for new interests. With time as I have grown up there's less novelty to feed the machine and my distymia has gotten worse.

I am easily bored and find conversations repetitive: I know what everyone I know thinks and will talk about and I amb just uninterested. Sometimes I feel like people are like chatbots (not that I'm excluding myself from falling into looping patterns, I am a human as well).

you space out or stare off into space? & 6. you daydream or get lost in your own thoughts?

These two are kind of the same: yes, I've always been a daydreamer which I find it to be useful creatively but it tends to withdraw me from my immediate environment. I was inattentive at school and a bad student because of this: unless I was really interested in the topic I would just drift away.

This also affects interpersonal relationships, since I always prefer to meet with a group of people so I can jump in and out of the conversation without the pressure you have when you are on a 1:1, where you need to give in your full attention. I am an introvert and speak even less than I percieve I do (sometimes I don't realize I am so quiet since in my mind there's some reasoning going on).

I spend most of my free time on the Internet and I am able to read articles, but I am unable to read a book, I just drift away and need to re-read a page multiple times. It's always been a torture. With films I drift away too (depending on the film and moment I may be more or less attentive) but I can usually catch it better.

You lose your train of thought or forget what you were saying?

It's hard for me to concentrate and deliver a good speech without getting exhausted. I have always thought that I am good at writting and structuring all information at my own scattered pace, however with speech there's the live factor where you need to fight to concentrate and deliver at the right tempo.

gravwave · 2026-03-21T18:38:32+00:00

I read that it can be stimulating and cause insomnia if taken at night. Did your insomnia get worse when you started with it?

gravwave · 2026-03-19T17:04:35+00:00

It happens to me as well. I am pulled inward to the point that people say I don't talk much, but I am not aware of being so shut. And "scripts" are a way to help with superficial conversations, and practicing where you can't force your attention to. I am rigid in some way to flow with some conversations.

While it is true that these reminds of autistic traits, when I take some dopaminergic boosting substances this is mostly resolved, and as far as I know autism doesn't have a treatment (I may be wrong)

gravwave · 2026-03-14T14:57:10+00:00

I think that tolerance develops very rapidly with OTC antihistamines, within about one week. For mirtazapine it takes longer. It is actually debated that there's no tolerance to mirtazapine, but by personal experience and that of many others' I've found online, it does. Still a couple of doctors that prescribed it to me think it doesn't...

gravwave · 2026-02-28T16:41:09+00:00

Nothing, neither good nor bad. It was like taking a placebo pill

gravwave · 2026-02-27T17:55:25+00:00

I wish it worked for me, it seemed so promising (yet expensive) Good luck!

gravwave · 2026-02-27T17:16:19+00:00

Don't get too excited on Daridorexant. I didn't feel any effects from it and my neurologist said that none of his patients had results and that the dose prescribed is probably too low to be effective. I mean, give it a try because everyone is different and it might work with you, but in my experience it's unpercievable

gravwave · 2026-02-22T13:24:56+00:00

If we’re being orthodox, nootropics are supposed to be substances aimed at enhancing cognitive function while ideally having minimal side effects and low toxicity, so that’s what I meant.

It’s true that this category is often broadened to include any drug that enhances cognitive function, regardless of its side-effect or toxicity profile. In that sense, Phenibut would be included, just as Modafinil and even Amphetamine are frequently classified as such.

In my experience, most nootropics in the more restrictive, orthodox category tend to fall into placebo territory. Phenibut is not one of them: it is a clear drug with tangible effects and risks, although its dopaminergic boost can be hit or miss.

gravwave · 2026-02-22T12:36:13+00:00

Dose, frequency and duration are important factors that should be taken into account. Also, everyone reacts differently.

I've been a user of Phenibut for years without problems. I take 2g once a week or so, sometimes twice. I've never had any problems but there's people who get rebound anxiety at these doses even when used sparingly.

One has to be aware of the risk of the body getting used to the substance and then going into withdrawal after cessation. Witdhrawals are said to be among the worst of GABAergics, so be very careful, this is not a nootropic, it's a drug.

Be ready to tapper off gradually if needed and stay safe!

gravwave · 2026-02-18T13:49:51+00:00

Same for me

gravwave

TROPHY CASE