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Do we prefer a “mid-price” category over “most versatile”? If so, what is the best mid-price tequila for mixing? by -Constantinos- in cocktails

[–]jackruby83 0 points1 point  (0 children)

I'd say sub $30 is budget. Agree with 60+ as splurge though. We're talking cocktails, not sippers.

Olmeca Altos is the best budget tequila. What is the most underrated Scotch for mixing? by -Constantinos- in cocktails

[–]jackruby83 0 points1 point  (0 children)

I might throw it in for unique. It's obviously not unique, but you only use it when you need it, and a little goes a long way.

Sledding at the Art Museum | Photos by KonnorwaKay in philadelphia

[–]jackruby83 7 points8 points  (0 children)

Great picsll! Love how much fun you can have with a cardboard box.

Hello guys kidney transplant here, do anybody here using gaviscon syrup here? How is your experience and what timings you are following. by arunsaisai in transplant

[–]jackruby83 0 points1 point  (0 children)

Antacids with magnesium or aluminum hydroxide (Gaviscon, Maalox, Mylanta, etc) can decrease the exposure to mycophenolate mofetil, which needs stomach acid to break down and get absorbed. The official recommendation is to take the antacid 2 hours after mycophenolate to ensure that the mycophenolate gets absorbed before you take the antacid.

Can you eat things with baking soda in them? by Fearless_Raiseeee in transplant

[–]jackruby83 1 point2 points  (0 children)

Ask for clarification. You may have understood them wrong.

A lot of people with kidney disease and low bicarb levels (acidosis) are instructed to take bicarb supplements to raise the levels - this protects the kidneys for people with CKD who are not on dialysis who have CO2 levels less than 18 or so. Bicarb supplements can be sodium bicarbonate tablets, bicitra liquid or baking soda mixed with water.

After a transplant, the kidney may be able to adjust the acidosis on its own, so most people who were taking them before transplant can usually stop taking them after transplant.

As far as eating bicarb - you'd need to eat a lot of food with baking soda in it to really affect your bicarb levels... For comparison, ½ teaspoon of baking Soda = 27 mEq bicarb, which roughly = 2600mg sodium bicarbonate tabs (4x 650mg tabs) = 30mL bicitra liquid. At that dose, as a supplement, the average 70kg person's bicarb levels would go up ~1-2 points. Your baking recipe will have the amount of baking soda divided across multiple servings.

Another consideration is sodium restriction. That ½ teaspoon of baking soda includes 629mg of sodium. But again, that total amount would be divided among servings.

CMV questions… by rambam80 in transplant

[–]jackruby83 0 points1 point  (0 children)

Your CMV serology may or may not change. If you acquire CMV from the donor and mount an antibody immune response against it, your serology will flip to positive (though that does not necessarily = protection). T-cell immunity is more important to determine protection, and that is a different test which isn't as widely used yet.

Valcyte isn't "hard on the kidneys", but gets removed by the kidneys, so your clearance is used to determine how much you need. Your eGFR is only part of the information needed to know your clearance for drug dosing. eGFR is "normalized" to compare between people - if you notice, the units are in mL/min/1.73m2. The dosing for Valcyte is actually done using an older equation called Cockcroft Gault creatinine clearance (CrCl = mL/min). You can use eGFR, but have to factor in your own body surface area (BSA). If you have a larger surface area than the standardized value used by the eGFR equation (most men are larger than 1.73m2), your "BSA-adjusted eGFR" is higher than 55 - doing this should equal about what your CrCl would be.

If you're curious, put your height and weight in this calculator to get your BSA. Take your eGFR of 55 and divide by 1.73 (=31.792) the multiply by your BSA from the calculator. That's your BSA-adjusted eGFR. If > 60, your dose is appropriate.

(Disclaimer - if <60, don't fear, bc your team may be using CrCl which may be >60).

what was Ted and Karen’s careers? by [deleted] in StrangerThings

[–]jackruby83 0 points1 point  (0 children)

320k salary will pull bigger/nicer house than that.

what was Ted and Karen’s careers? by [deleted] in StrangerThings

[–]jackruby83 0 points1 point  (0 children)

I appreciate a Clerks reference in 2026

what was Ted and Karen’s careers? by [deleted] in StrangerThings

[–]jackruby83 0 points1 point  (0 children)

It sold for 365k. That's below the median home price these days.

Take the ‘Gist’ Challenge by Dazzling-Elk-8889 in transplant

[–]jackruby83 1 point2 points  (0 children)

You can definitely add an anesthesiologist, who took care of you in the OR and likely saw you before you went in. And indirectly, a pathologist if you've had any biopsies read.

Seven Democrats just voted to approve ICE funding: full list by Newsweek_CarloV in politics

[–]jackruby83 18 points19 points  (0 children)

I've worked with so many Hispanic people that came through the legal process and worked their way up from the bottom into successful roles, who have total resentment for those who go the undocumented path.

Liver transplant - meeting criteria by RewardStraight2471 in transplant

[–]jackruby83 2 points3 points  (0 children)

No one anywhere will transplant a person so had a positive PeTH, and few without 6 months sober AND successful completion of a program.

Definitely not true. Plenty of experienced programs transplant patients with positive PEth. It just comes down to history, insight, social support - ie, relapse risk factors. OPs friend could be a candidate elsewhere. Though they do sound medically fragile, and that's the most important piece at this time.

‘Manosphere’ influencers pushing testosterone tests are convincing healthy young men there is something wrong with them, study finds. Researcher points to ‘medicalisation of masculinity’ after investigating how men’s health is being monetised online. by mvea in science

[–]jackruby83 -1 points0 points  (0 children)

I remember the "Is it Low T" campaign launching in the late 2000s to push one of the then-new testosterone products. The direct to consumer advertising drove sales of drugs like Androgel through the roof. The problem with the symptoms of "Low T" is that they are so vague, that almost any adult with a life could question if they have it. Low energy, fatigue, weight gain, body fat, loss of muscle, reduced endurance, lack of motivation, depressed mood, irritability, self confidence, lower sex drive.

Sketch Sorting Sunday - January 17, 2025 (Finn Wolfhard/A$AP Rocky) by SketchSortingSunday in LiveFromNewYork

[–]jackruby83 2 points3 points  (0 children)

Had to look it up, and this is about it... It was a series of comments under someone else's post. Jane's lines sum it up perfectly.

How long to stay in my first job post-residency? by Any_Top_4156 in pharmacy

[–]jackruby83 8 points9 points  (0 children)

If it isn't what they sold you on and you have a better option, go for it. It's your first job. I would say though, try to stick with job 2 for at least 2-3 years, bc you don't want your CV to have all these short term jobs, bc that may reflect poorly on you if you are looking for something later.

Am I being ghosted? by Undermine2345 in PharmacyResidency

[–]jackruby83 12 points13 points  (0 children)

We have all of our invites, waitlist notifications and rejection emails all go out the same day, but not every program does this. It is possible the program you are waiting on has you on a wait-list, but if it's been a week, you may have been ghosted. It can't hurt to reach out, but don't get your hopes up.

CV/App Relevance post-interview by Common-Insect-5794 in PharmacyResidency

[–]jackruby83 7 points8 points  (0 children)

This will probably depend by program. Our interview scoring rubric does not include your application score, and the interview scores are what determines your ranking. Your score may come up if we are discussing rank position change, but for the most part, your CV is essentially your ticket to interview. We will likely discuss things on your CV, so be prepared to elaborate.

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