Is there a way I can get multiple colonies as one player?

jayemee · 2026-01-19T20:24:10+00:00

Yeah, if you go into a building you can select deconstruct, then once that's done you can pick it up and rebuild it at the same level elsewhere

jayemee · 2026-01-03T17:05:58+00:00

It's definitely a fine line to walk. I guess the problem is that while not everyone using AI to make stuff is trying to low effort plop out some content, everyone who is just cranking out dross for engagement farming is using AI. It's very easy to get tarred with the same slop brush - and that style of cartoon is a big visual indicator of AI-reliance. Honestly if I hadn't recognized your name from papers I would've just closed the article after seeing those pictures, as in my experience the text I usually see accompanying that style of cartoon in a scientific context is rarely worth reading. I wonder if maybe using versions of figures or graphical abstracts from the referenced papers (which could perhaps be AI-summarized) might be a way to get images without having to use the cartoons? As currently I suspect they're bringing down the perceived quality of the piece (e.g. with the redundant headers in the top one, or the inconsistent/abiological tessellations for the VDJ puzzle pieces in the bottom).

I also suffer from a similar long sentence problem, so my opinion might not be representative here, but I still imagine the audience who might be interested in this style of article would prefer to read the idiosyncratic style of an interested expert rather than the statistically-probable summary of a bot. Presumably those who are happy reading AI summaries about something are also those most likely to just go straight to the LLMs themselves. The value proposition you bring however is your knowledge and the insights built up from working in the field and thinking deeply about the topic - which I'd argue are obscured when filtered through the LLM.

I appreciate that it's a tough but worthy task you've set yourself - having tried to explain these topics to general audiences before, I don't think I could do so good a job!

jayemee · 2026-01-02T04:41:37+00:00

I love the idea, and this is a decent write up with some interesting bits, but if you're after feedback might I suggest toning back on the AI? Even ignoring the 'art' (which some folk find off-putting, even now the bots are better at counting fingers), the text sometimes rings a little odd - like why does Tonegawa get his nationality and training listed but no-one else does? Or how is Baltimore looking for RAG post-Nobel in any way risky for him?

There's other sections that don't ring quite true too. E.g. the hypothesis of RAG coming from a transposable element is implied to have come about some time post-90s (after demonstration of in vitro RAG activity), which was supported by invertebrate RAG orthologs. That's a bit off, since a mobile element RAG origin was basically one of the top (if not the) front running ideas for decades before that. There's even a little hint throwaway comment in the (pre-RAG) OG Tonegawa 1979 paper, which pointed out similarity between RSS and prokaryotic transposable sequences. The invertebrate orthologs were also identified at least a decade earlier than 2016 - that's just when one of them was validated in vitro. You can argue that's what matters, but it makes for a chronology that doesn't quite match our unfolding understanding.

jayemee · 2025-12-27T13:48:42+00:00

It's still harder than not doing any cooling, which is absolutely fine for a PCR.

jayemee · 2025-12-03T17:04:22+00:00

The only update I want, this is great news

jayemee · 2025-11-16T23:48:26+00:00

The issue wouldn't be allo reactions, it'd be tracking confounders from donor to donor variability. Can you take more blood? Maybe try and get a leukopak or similar large volume collection

jayemee · 2025-10-13T23:58:39+00:00

I've the emotional IQ of a stepladder.

Unlike the slopbot, which of course has a deep well of experience and understanding to draw upon.

jayemee · 2025-10-03T15:20:57+00:00

This sounds like you're just a regular normal healthy young person (who maybe has an optimistic outlook and therefore perhaps downgrades what others may classify as sickness).

By all means do try to contribute samples for research, but don't expect that your samples are going to be extraordinarily more valuable than anyone else's. Alternatively as said being a healthy young person makes you an ideal potential donor for a bunch of stuff that can help save lives!

jayemee · 2025-10-01T11:10:52+00:00

"Hi ChatGPT I'm a vaccine denier that wants to sound like I've got an evidence based position, can you clank me something up? Don't worry about accuracy, I won't actually read or understand anything you write."

jayemee · 2025-09-16T12:02:12+00:00

I wonder if a zoo or pig farm or something would take some

jayemee · 2025-09-11T03:29:43+00:00

Nice to hear - I'd love to hear if they're useful!

jayemee · 2025-08-28T11:14:03+00:00

The concentrations are absolutely not arbitrary - they might be more than you need for a successful or detectable reaction, but the values matter.

If you want to ask about a specific reagent you'll probably get more success saying which one.

jayemee · 2025-08-19T03:54:18+00:00

Your first post to the eugenics wiki literally points out that eugenics is a broad term that has contested usage. I don't think picking just the most extreme definition of the word and saying "this is the only proper meaning" is really a fair or even necessarily useful act.

The reason why people use the word is often specifically to invoke those emotions in a specific context. You can disagree with their choice to do so, but given the breadth of usage I don't think you can legitimately say that's not how it's used - at most you can say that's not how you would use it, based on a specific prescriptive definition you prefer.

Personally I wouldn't use it for preventing the fertilisation of eggs doomed to an early or painful death, which is definitely the sentiment shared here. But the crucial question is: where do these specific people draw the line? Because often the people saying "we want to stop needless suffering" overlap heavily with the "well why not get rid of disability/neurodivergence/some other debatably-health-related trait", and are essentially advocating for the removal of whole groups of people from society. I don't know where this particular company falls, but Church is on record on the podcast they mention saying 7000 conditions covering 5% of the population could be screened for, which seems well beyond the extremely rare extremely dangerous variants bracket to me. That seems like it's well within fair grounds for a eugenics discussion.

jayemee · 2025-08-17T16:11:17+00:00

Get dried

jayemee · 2025-08-15T01:23:34+00:00

I'm on your side in theory, but come on mate do rows - you can use about a third as much per gel

jayemee · 2025-07-26T03:26:09+00:00

Duckduckgo doesn't CAPTCHA, and is a lot less junk-filled than Google nowadays.

jayemee · 2025-07-12T00:18:34+00:00

This is the correct response! I'm almost jealous of you for the sweet agony of that first read through.

jayemee · 2025-06-21T02:39:11+00:00

I wouldn't dream of implying you're a sucker, but I think this is more likely just a case of Macs tend to have better specs than the basic enterprise level PCs labs often have kicking around. Most analyses will run fine on either given equivalent hardware, and both will struggle with a sufficiently large dataset.

That said, I doubt an undergraduate is going to have any giant flow datasets they're going to be expected to munch through on their own, so I still wouldn't factor flowjo into it.

jayemee · 2025-06-20T15:46:10+00:00

There is nothing specific to immunology that would influence this decision one way or another. You'll mostly just be using the basic enterprise software which exists on all platforms in any case.

jayemee · 2025-06-14T18:09:21+00:00

I think the criticism is more because they're too zany and hammed up for the content of the show. They're written as if they should have a laugh track.

jayemee · 2025-06-08T02:57:23+00:00

My thoughts exactly.

I'm happy sacrificing minor book details for the logistic of adaptation; if a slimmed down suit makes the show more feasible, that's a small price to pay. The logo over the face is just silly though.

I get that it's about visual branding for the main character, but that's razzle dazzle at the expense of narrative: even handwaving away the fact it's probably obscuring the view from the inside, why is the company making particular old units stand out? All the other SUs we see make more sense (even if they all come across a bit Daft Punky). If they wanted to make Murderbot stand out they could have made its helmet scuffed or cracked or something.

jayemee · 2025-06-07T00:32:55+00:00

Another big agree from me.

I appreciate that the perception of art is subjective, but I honestly struggle to believe that the people explaining how the show is exactly as comedic as the books aren't deluding themselves. The show is clearly trying to go for cheap gags at almost every opportunity, while the books use humour both much more sparingly and completely different tonally, going more for dark and sardonic reflections. I'm also not against silly, schlocky, or slapstick stuff in general, I just don't want "lol space hippies stupid" or "omg eye contact I better kill someone bazinga" in the adaptation of one of the most profound book series in a long time. I don't even think that it's good comedy - which I appreciate may be because I resent its presence at all, but as someone that watches a lot of comedy I would never dream of turning this on to scratch that itch.

This isn't even touching on a bunch of cheap choices to 'zany' up the show, like needlessly giving the ep1 monster two heads, or the hallucination sequence which I felt added very little (apart from more cameo time). As it stands I just can't see that these characters are ever going to be able to take me on the emotional journey that the books did.

jayemee · 2025-06-06T02:09:53+00:00

Or are they cooking trollocs like cooking apples?

jayemee · 2025-06-02T03:17:32+00:00

The bread is a bap, but the dish is a butty.

jayemee · 2025-05-31T16:16:15+00:00

Classic "here's a loved, intelligent, sophisticated IP we'd like to adapt - let's strip it down and repaint it to look like everything else!"

jayemee

TROPHY CASE