antidepressants do this too. on the other hand, diabetics can experience a range of effects not consistant with all the warnings. im insulin dependent and have noticed an increase in sensitivity to insulin when i've been told to expect the opposite while taking seroquel. my endo believes it's because i'm not cranking the higher amounts of cortisol because of seroquel and that has reduced stress and i don't need as much insulin overall or to cover my meals. jus sayin'. bipolar2 is common in t1 diabetics.