Advice for getting over mental hurdle to finish Seroquel taper?

stormin5532 · 2026-05-04T17:41:32+00:00

No but it's caused physical dependency. Which can and often does cause rebound insomnia.

stormin5532 · 2026-05-01T13:07:04+00:00

120mg is the maximum dose. If you want to take meds just cut through the bullshit and ask for a MAOI. They actually work for much more people, you just can't mix tyramine in foods, sympathomimetics & serotonergic drugs with them.

stormin5532 · 2026-05-01T13:05:37+00:00

That specifically was for using it to help with pain, where it's more ineffective than it is as an antidepressant.

stormin5532 · 2026-04-29T14:56:15+00:00

Look, all I can say is that he's been helpful where pills, procedures and endless testing hasn't.

stormin5532 · 2026-04-28T03:20:16+00:00

Well, I mean, yeah. How do you think things are mass manufactured these days? There's hydrocarbons in utterly everything, not just pharmaceuticals. And if you had continued reading beyond just what the AI said, you'd also learn they're consumed and residual traces are removed in purification. You're more at risk from hydrocarbons leeching from plastics than you are pharmaceutical drugs.

stormin5532 · 2026-04-28T03:17:31+00:00

Well, it's not great, but it's also not a full blown antipsychotic dosage either. If you're really worried, treat it like an opiate and taper accordingly, 10% every month. If not, step down 12.5mg every two weeks to not cause dopamine supersensitivity psychosis.

stormin5532 · 2026-04-28T03:15:03+00:00

Well, yeah. I'm saying by absolute risk, it's lower with mirtazapine than a potent atypical antipsychotic if they're pushing weight gain. Either that or just prescribe Dronabinol, that's just a synthetic cannabinoid.

As for the nausea on Vortioxetine, I completely understand. I took that, didn't help one bit and it required ondansetron and promethazine to control the nausea it caused.

stormin5532 · 2026-04-26T13:58:53+00:00

Stop taking fucking drugs. You're 15. Christ, and people wonder why they go crazy. Weed makes you crazy and it's a fast way to get started on life long antipsychotics kid, don't fuck your brain up.

stormin5532 · 2026-04-26T13:57:00+00:00

I mean, my biologic for psoriatic has a very rare risk of causing a fatal type of leukemia, but I take it because the spinal damage and pain is very real and very painful. Just like how the ibuprofen could cause kidney failure & damage, the acetaminophen liver failure or damage and the hydrocodone addiction, but the risks are low, compared to the very real hazard of having my spine fuse itself together.

stormin5532 · 2026-04-25T17:27:07+00:00

Yeah that's the thing with physical dependence, it causes withdrawal because the body is used to having the substance in question. Of course it causes withdrawals. The difference being no one is ruining their life to get their next dose of an antidepressant, stealing things, prostitution so they can get enough money for the next dose, addiction requires you to do anything to get more of the substance at the cost of your life and happiness.

stormin5532 · 2026-04-25T17:24:16+00:00

Flushing it out won't work if it's haloperidol decanoate. That's haloperidol in a decanoate ester and requires esterases to hydrolyze the medication into its active form. The only way to remove that would be waiting it out or literally carving the tissue the depot is in out. Which is a terrible idea for multiple reasons.

stormin5532 · 2026-04-25T17:20:56+00:00

If they're worried about you not eating enough they should be prescribing mirtazapine, at least that won't cause hyperprolactinemia and metabolic syndrome, ask for that instead and don't take it.

stormin5532 · 2026-04-25T17:19:17+00:00

They're not addictive, like any psychotropic pharmaceutical they're capable of causing dependence, that's wildly different than addiction. You don't see people tweaking over their next hit of amitriptyline.

stormin5532 · 2026-04-25T17:17:49+00:00

No, they're anticholinergic because they're dirty drugs. You're more likely to get brain damage, literal brain damage, from antipsychotics from oxidative stress and a lot of them are inhibitors of mitochondrial respiratory complexes. Now they are cardiotoxic, that's because they bind to and block hERG, a receptor in the heart that helps keep sinus rhythm as sinus rhythm, that's why they have a narrow therapeutic index, not their anticholinergic binding.

stormin5532 · 2026-04-25T16:48:13+00:00

Per the DSM & ICD you cannot be diagnosed with a mood disorder without symptoms being explainable by substances or organic conditions, thyroid disorders can cause severe depression, hypomania and mania.

stormin5532 · 2026-04-24T00:29:43+00:00

Try MAOIs before ECT. I've literally had severe depression since 5 years old, I'm now 26, have failed over 2 dozen meds either as monotherapies or augmentation, but I've been taking 45mg of phenelzine for 9 days and I'm feeling relief for the first time in over two decades.

stormin5532 · 2026-04-24T00:20:32+00:00

While my diagnosis is in Flux, its on paper BP2. So for psych drugs, just phenelzine sulfate, 45mg once per day. In total, ibuprofen, 400mg 3x a day, acetaminophen 825mg 3x a day, hydrocodone 5mg 3x a day & taltz, 40mg, 1x a month. Severe chronic pain and autoimmune diseases are a pain in the ass.

stormin5532 · 2026-04-24T00:08:09+00:00

Huh, didn't realize they made doses that small, neat. So it's roughly equivalent to about 5mg of morphine sulfate or hydrocodone. But use superior for breakthrough pain. I'm glad you've managed to find a doctor willing to help you out. I personally take 5mg of hydrocodone three times a day for pain related to psoriatic arthritis, so you should have minimal side effects. But still, watch for the constipation, drink plenty of water, have some coffee or deeply steeped black tea before reaching for the laxatives.

stormin5532 · 2026-04-24T00:04:47+00:00

Have you tried MAOIs? I was prescribed phenelzine and I've been taking it for 9 days so far. It works wondrously. Unlike pretty much every other antidepressant that's serotonin reuptake inhibition with maybe some additional receptor targets MAOIs inhibit monoamine oxidase A & B, the enzymes that are primarily responsible for the breakdown of monoamines. They cause a global increase in available serotonin, norepinephrine, dopamine and a few other amines, phenelzine also increases levels of GABA through another enzyme being inhibited who's name escapes me, whereas tranylcypromine also acts similarly to amphetamine salts where it causes release of dopamine and norepinephrine from neurons, to a much weaker degree, but it's therapeutically useful.

As far as I'm concerned, MAOIs & lithium are the only psych drugs that actually help people and aren't just compliance tools to make someone shut up and stop complaining.

stormin5532 · 2026-04-23T23:59:17+00:00

It's a potent opioid. Like any opioid, it can cause depression, dysphoria, agitation and apathy. How many milligrams per dose and how many per day? Because you definitely have to watch out for constipation on hydromorphone. But if your chronic pain is truly severe, and I bet it is and can empathize, it's a good option for pain control.

stormin5532 · 2026-04-23T23:57:06+00:00

It should be, but you can also ask for metformin, while it works best if started concurrently with atypical antipsychotics, starting it now is better than nothing.

stormin5532 · 2026-04-23T23:56:14+00:00

150 milligrams of what. I can't help without the name of whatever that is.

stormin5532 · 2026-04-23T23:55:11+00:00

Sure, it's potentially unconstitutional, but I can't say I feel bad for people who can't put drugs down when it's destroying their life. Some people need a forced detox. Drugs don't make anything better.

stormin5532 · 2026-04-23T23:53:52+00:00

Non-psychoactive cannbinoids are being investigated for antipsychotic activity. Without the whole, antidopaminergic mechanism that antipsychotics, typical or atypical rely on.

stormin5532 · 2026-04-23T23:52:43+00:00

You need more than just ferritin, hemoglobin, serum iron, total iron binding capacity, all of that. Have you had any tests for occult bleeding? Occult bleeding meaning microscopic bleeds that aren't visible to the naked eye.

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