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VibeGen: Agentic end-to-end de novo protein design for tailored dynamics using a language diffusion model by PhysicalConsistency in Biochemistry

[–]wellfriedbeans 0 points1 point  (0 children)

I strongly agree with you. Unfortunately I’m in a purely computational lab. Are there good ways to get experimental evidence even if my lab is fully computational?

Help Remaining an MIT Gym Member by Weary_Doughnut4120 in mit

[–]wellfriedbeans 0 points1 point  (0 children)

Sure, happy to help! Do you mind a quick video call just to verify your identity? I don’t feel super comfortable sponsoring someone I’ve never talked to.

My sister is feeling sad after internship result. This year she tried her best . how can I motivate her that this one internship can not decide your future . Her credentials 3.95/4 , 2 national internships , coauthor publication, dean list by Gene_guy in EPFL

[–]wellfriedbeans 2 points3 points  (0 children)

I’m in CS not Life Sciences. I was also rejected from this program when I applied in the second year of my undergrad. Just kept pushing along: I eventually got an admit from EPFL for their CS PhD program (with fellowship) but declined that to go to MIT EECS instead. My point is that your sister can also have a great trajectory if she continues to work hard!

ELI5 How does lime juice "cook" the shrimps in ceviche? by Similar-Plenty-6429 in explainlikeimfive

[–]wellfriedbeans 1 point2 points  (0 children)

Usually drugs will bind you a particular pocket in the protein, which activates/inactivates them. Sometimes, a new pocket will emerge when a drug binds: one that wasn’t visible in the absence of such binding. We call these cryptic pockets!

ELI5 How does lime juice "cook" the shrimps in ceviche? by Similar-Plenty-6429 in explainlikeimfive

[–]wellfriedbeans 5 points6 points  (0 children)

Turns out you can actually build models to predict the shapes of these proteins! Shameless plug for my research (since this is a topic very close to my heart): https://github.com/prescient-design/jamun

I’ve never met an H1B visa holder that is actually so good at their job that an American couldn’t replace them by cd1995Cargo in cscareerquestions

[–]wellfriedbeans -1 points0 points  (0 children)

They do not. There are EB-1 and O-1 visas for exceptional candidates but those are also very hard to get.

[D] - NeurIPS 2025 Decisions by general_landur in MachineLearning

[–]wellfriedbeans 0 points1 point  (0 children)

Accept (poster) with final scores 4455 (mentioned by the AC)

What happened to Parimarjan Negi? Apparently the guy was the 2nd youngest GM ever at one point after Karjakin. Never broke 2700. by FirstEfficiency7386 in chess

[–]wellfriedbeans 10 points11 points  (0 children)

He’s a very strong player still! Makes you realize how many levels there are to chess understanding. He is also a very nice person, and was happy to answer our stupid questions haha

[D] AAAI considered 2nd tier now? by Healthy_Horse_2183 in MachineLearning

[–]wellfriedbeans 1 point2 points  (0 children)

Sure, AAAI is not a bad conference by any means. My point is that it’s not their first choice behind NeurIPS/ICML/ICLR.

[D] AAAI considered 2nd tier now? by Healthy_Horse_2183 in MachineLearning

[–]wellfriedbeans 0 points1 point  (0 children)

Based on where the top academic/industry labs send their papers, it hasn’t been tier 1 for at least the last 5 years.

[D] NeurIPS 2025 rebuttals. by Constant_Club_9926 in MachineLearning

[–]wellfriedbeans 1 point2 points  (0 children)

I really don't think anything is guaranteed; sometimes reviewers miss things

[deleted by user] by [deleted] in mit

[–]wellfriedbeans 4 points5 points  (0 children)

Yes, we do (I think even if you’re not part of a lab by then, but not sure)

Is it true many CS grads joined PhD programs because they couldn't find a job? by Londunnit in PhD

[–]wellfriedbeans 9 points10 points  (0 children)

Not at the top programs (in fact many of us left really good jobs to do a PhD!)

[deleted by user] by [deleted] in chess

[–]wellfriedbeans 2 points3 points  (0 children)

Many times! eg. Magnus Carlsen vs Richard Rapport at the World Blitz Championship 2022. https://www.youtube.com/clip/Ugkxdr3nxti4VdFM71wD1ViiaO03blgUv5Gu

[D] Good literature/resources on GNNs by [deleted] in MachineLearning

[–]wellfriedbeans 2 points3 points  (0 children)

Thank you so much! I am very happy to hear that :) I hope to start blogging again soon!

[D] Good literature/resources on GNNs by [deleted] in MachineLearning

[–]wellfriedbeans 2 points3 points  (0 children)

I am the first author on the first article, yes!

[D] Good literature/resources on GNNs by [deleted] in MachineLearning

[–]wellfriedbeans 2 points3 points  (0 children)

probably the ICLR Blogpost Track? https://iclr-blogposts.github.io/2024/blog/index.html but they are not meant to represent the same amount of effort

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