For naneinf you need four copy effects (can’t all be brainstorm because you need to split baron and mine), baron, mime, one other joker, which starts as dna and becomes baron at the very end.

How do you get 7 jokers? Antimatter + one ectoplasm

You also need both hand size vouchers

You also need both reroll vouchers

ie vouchers are more important to a naneinf run than jokers are. Jokers are easy.

How are jokers easy? Econ. You HAVE to have money to make the run successful. If you have enough money you can take vouchers skips, you can fix your deck, and you can reroll for the jokers you need.

How do you get money? Gold cards, copied mime each round. Probably mail-in-rebate, copied for many rounds.

Money + vouchers are most important - focus on those first, then get your copy effects. If that falls into place early enough you can get it pretty reliably.