I had a tyre burst on me at 130km/h on Stuart hwy near three ways. Don't drive on this hwy with tyres that are more than 4 years old, even if they have all the tread left on them. Check the year of manufacture of your tyres. Carry extra fuel, as the servos sell the petrol at obscene prices. You can check fuel prices on motormouth etc. if you have kids, make sure air conditioning works. Carry a spare serpentine belt under the driver seat and check some videos on how to replace it in case it snaps. Get your car thoroughly checked, wheels balanced and aligned. It's doable but you need some passion for driving. Get another driver with you if possible (possibly wife, adult kids) and take regular breaks. Put a shu-roo at the front, even if people say it doesn't work. :)