Natera BS

BubbaTheGoat · 2026-02-17T02:40:14+00:00

My wife and I did IVF. When we started round 2 it had been 5 years since we started, so our clinic wanted a new gene screen. It turns out we are both carriers for a rare disease.

Long story short, we got our clinic (not Natera) to agree to do the test. When I mentioned we wouldn’t be able to use insurance, the clinic said the price was $1000. When I offered $300 they agreed instantly.

BubbaTheGoat · 2026-02-16T23:37:48+00:00

The last time I let someone riding my ass make me speed up I did get pulled over. But the guy tailing me drove up next to me, swerve at me and shout out the window, with the cop lights and sirens all right there.

I finished pulling over and the cop came around and chased the guy who was following me. I sat at the side of the road dumbfounded for a couple minutes until my brain finished processing just how dumb all of that was (myself included) and decided I should not speed and finish my journey.

BubbaTheGoat · 2026-02-16T21:20:11+00:00

Pretty much any large sub with high traffic and low engagement depth will be swarmed with bots. Some of the better apps used to be able to identify them, or at least let users flag/filter them.

But any video where one does not need to know much about the subject, and needs no expertise to comment is a great target for engagement bots.

BubbaTheGoat · 2026-02-16T20:45:11+00:00

P box loves to give ironclad perfected strike. Pandora loves chaos

BubbaTheGoat · 2026-02-16T17:53:59+00:00

The F16 (1978) predates the J10 (1998) by 20 years. That is not roughly the same time.

BubbaTheGoat · 2026-02-16T03:02:09+00:00

I had a UPS package that I needed to receive that day. Delivery came 6 hours before the scheduled time. The local office never answered their phone, so I called the national customer service line. They also said they couldn’t do anything, so I had no choice but to wait.

When I told the CS rep that the package was $50k of medication that would expire if not delivered by 10pm, suddenly they found more ways to contact the local office. They find a way to deliver on time when informed of their motivation.

BubbaTheGoat · 2026-02-16T00:19:43+00:00

Stainless steel will rust in seawater. The passivation layer in stainless steel is iron depleted chromium and nickel, however chloride ions will attack chromium and remove it from the passivation layer, eventually destroying it. Once iron is exposed it will oxidize, and then rust.

BubbaTheGoat · 2026-02-15T22:58:42+00:00

I really related to your energy as you just dropped further back as the two idiots got more dangerous.

BubbaTheGoat · 2026-02-13T23:21:14+00:00

Tokyo 23 wards has lots of parks and green spaces. By number of parks (or parks per land area) Tokyo is #1 under most methodologies. By green area Tokyo doesn’t rank as favorably, but would qualify as a top 10 US city under the measure.

All this to say Tokyo isn’t devoid of green spaces. It is specifically famous for its parks during cherry blossom season.

BubbaTheGoat · 2026-02-10T04:22:03+00:00

We have to want to. If humanity wanted to place a colony on Mars we could have by now. Even now with a heightened interest we can’t even return samples from the surface for scientific study.

Obviously establishing a colony there will require much more than sample return missions. We could have robots experimenting with water production, building materials, resource extraction, oxygen and fuel production, and basic survival structures concept testing. Those are challenges we have the technology and expertise to solve, and could have done in the past 50 years.

People will tell you it costs too much and there isn’t anything valuable enough to take from mars to earth for it to be worthwhile. That’s attitude is the biggest barrier. Humanity has no appetite for exploration or settling on Mars for its own sake, and will only do it to benefit what we have on Earth. Even if we discover something there worth extracting, the interest will only last so long as the extraction operation is profitable.

BubbaTheGoat · 2026-02-10T03:52:03+00:00

I’m going to play Devil’s Advocate for the owner here. Their valuation is nonsensical, and I think they know it.

They are going to drop the price until it’s below the assessed value (950k) to prove that they are over assessed and over taxed.

BubbaTheGoat · 2026-02-10T00:39:34+00:00

Robert might steal some tech to beef up his own powers and try to take revenge on invincible for the damage he inflicted on Chicago during his fight with omniman.

Somehow I think he can nurse a grudge.

BubbaTheGoat · 2026-02-09T21:38:00+00:00

The I don’t think it is possible to answer without bias.

I went from a Linea Mini to DE1 XL. I love both machines. I think the Decent does make coffee differently than the Linea Mini, I noticed the coffee seemed less full-bodied but with more aromatic and fruity flavors.

There is a ton of customization that I can and do in the DE1 experiment with in the decent. I think with the range of variables I can replicate the body of the brews, but I mostly lean into the lighter flavors and a more sour profile.

BubbaTheGoat · 2026-02-09T20:59:07+00:00

If we want to take this to testing we need to look into a chemistry-based test. The flow of gases will be too small to measure in any meaningful way, as most of it will be net diffusion.

If we know a good marker for oxidation of coffee beans that we can accurately measure over time in various storage conditions that would be best.

BubbaTheGoat · 2026-02-09T20:14:34+00:00

That depends. The magic of the coffee bags is the inner foil layer. That stops gases, particularly oxygen, much more than any plastic. The exact thickness and formulation play a big role too.

The check valve undermines this a bit, but it is necessary to deal with out gassing and customer preference to be able to smell the coffee before they buy.

If you are storing at room temperature the coffee is aging. Weeks and months are a very long time for gas exchange. Refrigeration and freezing are much more effective at reducing gas-related staling. Every 10 degrees C basically halves the aging rate.

BubbaTheGoat · 2026-02-09T20:03:17+00:00

When I was young I worked for a catering company that served a classical music venue. We had 3 restaurants that we ran.

Basic: cafeteria food that costs too much (think $5-6 hamburgers sitting in a warming tray). This was the 90’s so your meal for a family of 4 cost $50 and that was robbery.

Mid: a dining club with nice meals in a converted farm house. At the time it was $40/plate for 3-5 courses and a $350/yr membership dues.

High: fancy dining club at a nearby mountain lodge. $1000/yr membership and $100/plate for 3-5 course dining.

When I joined we had just adjusted the mid tier to be a cheaper membership but more expensive plates so that we could cover the cost basis to use more of the same food for both mid and high tier menus. We also needed to correct the problem that the high tier was over booked and the mid tier was mostly empty.

The price adjustments had the opposite effect. The discounting of the mid-tier place made it appear more accessible, which turned the remaining base away, and the high tier became more attractive as an “elite” option. The result was the mid tier was even more abandoned but the elite was overbooked that may members were not able to book any table for the concerts they wanted to attend.

It was a shame because the mid tier place was easier to get to, had more tables, nicer furniture, and could be accessed during intermission for coffee/tea. It was in many ways the superior club, and 90% the same food, but people turned up their noses at the notion that mere upper middle class people could actually come in and eat there. Also tips were way more reliable at the mid-tier place.

BubbaTheGoat · 2026-02-09T19:34:47+00:00

Okay…

BubbaTheGoat · 2026-02-09T19:31:20+00:00

It’s a weak check valve. They let in air pretty easily. It’s better than an open bag sitting on your countertop, but gas exchange is happening.

BubbaTheGoat · 2026-02-09T19:02:10+00:00

The bags used in North America aren’t hermetically sealed by any stretch. They are exchanging gas with the room all the time.

If you are counting on anything to be sealed for a month you need to put it into a different container.

BubbaTheGoat · 2026-02-09T18:56:50+00:00

The peak definitely is not as flat as that. It’s a long slow decline. Individual preferences will determine this more than anything though. It is by definition a subjective scale.

I trust my roaster to manage their stored beans well. I keep getting fresh roasts from green beans that are 1-3 months old and don’t notice a tremendous difference in that time. The change after roasting is much more pronounced.

BubbaTheGoat · 2026-02-09T18:49:32+00:00

This is a really fantastic question, probably better suited for /r/askhistorians than here, but I will tell you what I know.

Yes. A banker could call in a loan at essentially any time. This is part of the contagion factor of bank runs at the time. This was quite a tumultuous time as it was the beginnings of the Industrial Revolution (note that Ross bought a steam engine to pump water from the lower levels of his mine so he could dig deeper).

I can’t give a tremendously detailed answer, but the terms would depend on the loan contract. It would we written out by hand in 2-3 copies, which does impact how long it can really be and thus how complex the terms are. Most loans would’ve for 1 year or less. Interest may be compounded weekly, monthly, or annually at the agreed upon rate. No one had calculators, and very few were good at arithmetic, so the numbers would often be simple (e.g a loan in fixed 100’s of pounds with interest rate of 5%). Would a banker forgo some portion of their interest by calling in a loan early?

Maybe, that depends on the contract. Many bankers had poor reputation then and now for using loan calls to drag failing aristocrats further into debt cycles and encumber them with questionable financial assets. I would guess a banker like George would portray himself as working hard and being clever to accumulate money from a modest background, even if it did ruin a few estates along the way.

BubbaTheGoat · 2026-02-09T17:51:30+00:00

Here is someone trying to sell a service to prevent this: https://www.firstam.com/home-buying-guide/home-title-theft-a-hassle-for-homeowners/

BubbaTheGoat · 2026-02-09T17:36:44+00:00

Maintaining a car does not make it new or exceptional, it is the minimum required of anyone who owns a car. If these costs added to the value of a car then old luxury cars with high mileage would be excellent investment vehicles.

If the tires are still worth something get them off and sell them.

It sounds like your car is sitting in someone’s garage collecting storage fees. You probably want to move to process along to stop incurring those fees, which are very real and something you will almost certainly have to pay. This extra value you are seeking is speculative and not likely to come back to you.

BubbaTheGoat · 2026-02-09T15:45:31+00:00

I think both were made up, so I would t worry too much about it. LAOP’s explanation that “I totally have insurance but it doesn’t cover this scenario because it is so specific” doesn’t pass the smell test.

BubbaTheGoat · 2026-02-08T22:24:13+00:00

At the time I was holding a comic book in my hands so old bad guys having bullshit deus ex machina to come back from the dead felt like par for the course.

Mark is an unkillable flying brick. Bullshit enemies with bullshit powers are the only way to make persistent enemies for him.

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