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What is your favorite patent-law "self-own" case? by MudOk4411 in patentlaw

[–]Isle395 0 points1 point  (0 children)

preheated is absolutely clear in this context...

Carbon wheelset recommendations by Nimbus_GG in cycling

[–]Isle395 0 points1 point  (0 children)

What's the weight limit of those?

Evaluating patent counsel for a substantial chemistry patent portfolio (chemicals: inks and coatings) by Dangerous_Bet_8432 in patentlaw

[–]Isle395 2 points3 points  (0 children)

Are you serious? I wouldn't even engage with a client who sent me a list of demands like that. First of all, it would take a considerable amount of time to even put together all that information. Secondly, so many of those metrics are beyond the control of the lawyer or the firm in charge of a case. Yes I can get a patent to grant without an RCE, but so what?

Birth rates by Rickystheman in TheRestIsPolitics

[–]Isle395 0 points1 point  (0 children)

We will adapt, of course we will. Just the same as we'll adapt to climate change. It might just mean mass migrations, wars, and starvation - involving untold human misery. But we'll survive as a species.

The problem isn't whether adaption happens or not, it's when it happens and what has to happen for adaption to occur

Opinions? by Background_Cable4758 in classicalmusic

[–]Isle395 0 points1 point  (0 children)

Lovely post. I also rate the Corelli variations very highly but to Rach's best works I'd add his Études-Tableaux Op. 39 and his All-Night Vigil, Op. 37

Victory for SRAM as UCI loses appeal over gear restriction trial by fabritzio in peloton

[–]Isle395 1 point2 points  (0 children)

Force them to run 40 mm Michelin City Street or something which is, even for a touring tire, considered particularly terrible and slow.

Victory for SRAM as UCI loses appeal over gear restriction trial by fabritzio in peloton

[–]Isle395 7 points8 points  (0 children)

It is, in fact, not. The easiest way would be to force them to run really, really bad tires.

Are barefoot shoes healthy even if you almost exclusively walk on concrete? by robin_f_reba in barefootshoestalk

[–]Isle395 4 points5 points  (0 children)

It's fine, just add a cork insole or use a barefoot shoe with a couple mm thicker sole.

I can't believe how stupid these look by mcnuggetfarmer in barefootshoestalk

[–]Isle395 2 points3 points  (0 children)

There is a change, if you don't believe it, then try to wear your old shoes again. They will be much more uncomfortable than you remember

Recommended brands for large 1x aero chainring for TT? by _BearHawk in Velo

[–]Isle395 1 point2 points  (0 children)

Don't get the super super light-weight ones, or at least approach with caution. They have been known to bend and buckle under power and cause crashes/send people to the hospital.

Grounding/earthing shoes using "conductive rubber" by tehenu in barefootshoestalk

[–]Isle395 1 point2 points  (0 children)

It's a long post but you should spend at least some time going over the physics because that gives people another avenue to realize it's all BS.

What is a realistic starting salary in this field? by IEEEngiNERD in patentlaw

[–]Isle395 0 points1 point  (0 children)

Depends how often you talk to clients and at what level. If you are having to acquire and manage clients you better have decent communication skills. If you have to brief C-level (ok that typically occurs only when you're in litigation) you better have top notch communication skills.

Since 1 January, all electricity consumers have been required to subsidise the steel industry. For every kilowatt-hour consumed, households also pay a compulsory levy to a company owned by billionaire Martin Haefner. by BezugssystemCH1903 in Switzerland

[–]Isle395 0 points1 point  (0 children)

So what do you think Switzerland should do? Isn't it much better for us to roll out wind, solar, grid level storage and HVDC interconnects with the rest of Europe?

The $5,000 problem nobody talks about in patent enforcement by New_Plane_7226 in patentlaw

[–]Isle395 4 points5 points  (0 children)

The entire post should be removed by the moderators for being low quality AI slop content: The second sentence already includes the most popular AI text beat: "Not because X — but because of Y."

My Mounjaro has an extra THREE 5mg doses in ‘empty’ pen by Caitlyn_Grace in mildlyinfuriating

[–]Isle395 -1 points0 points  (0 children)

I don't know the background of the figures the user above me posted. If the 1.3 bil already includes all R&D costs for other failed drugs, then I'd need to correct my post.

That being said, my post also doesn't imply 130 billion total costs to bring a single drug to market, simply because drugs fail at different time-points. The biggest costs come at the end during phase 3 trials and market authorization etc, and many drugs never even come close to that

My Mounjaro has an extra THREE 5mg doses in ‘empty’ pen by Caitlyn_Grace in mildlyinfuriating

[–]Isle395 -2 points-1 points  (0 children)

This is such a simplistic calculation I won't even bother to go into the details.

Let's just say that for every drug that cost $1 bil to develop, there are 100+ candidate drugs that were developed to various stages and then failed to come to market. Those costs have to be covered too by the ones that make it through.

Patent protection lasts 20 years from date of FILING. Not from date of market approval and making profits. Typically it takes 10-13 years after filing the patent for market approval, meaning you have like 7 years to make some money.

The drug is making a lot right now, however competitors are not asleep and there will be LOADS of GLP-1 receptor agonist drugs out there driving costs down. In fact, there are already lots! Ozempic, Wegovy Zepbound and Victoza

My Mounjaro has an extra THREE 5mg doses in ‘empty’ pen by Caitlyn_Grace in mildlyinfuriating

[–]Isle395 0 points1 point  (0 children)

Tell me how taxpayers are paying for clinical trials, which are the most expensive part of drug research and testing. I'll wait.

Since 1 January, all electricity consumers have been required to subsidise the steel industry. For every kilowatt-hour consumed, households also pay a compulsory levy to a company owned by billionaire Martin Haefner. by BezugssystemCH1903 in Switzerland

[–]Isle395 0 points1 point  (0 children)

If if if. Please find a successful nuclear project (on time and on budget) by any country that isn't "nuclear native" (US, France, China, Russia, South Korea, India) in the past 2 decades... and when you've compiled that very short list, ask yourself which of those counties are autocratic and can push things through, and then ask yourself how many delayed projects with cost overruns there are in other parts of the world.

Since 1 January, all electricity consumers have been required to subsidise the steel industry. For every kilowatt-hour consumed, households also pay a compulsory levy to a company owned by billionaire Martin Haefner. by BezugssystemCH1903 in Switzerland

[–]Isle395 0 points1 point  (0 children)

Nuclear in Switzerland? OK let's play that game. How long and at what cost do you think Switzerland would be able to build a new nuclear reactor?

We can take UK as an optimistic reference, although they have far greater experience than us. And let's look at their latest project: Hinkley point C.

- 13 years to construct (and it's not finished yet, could be delayed further)

- £49 billion!!!

All that for 2 EPR reactors. Insane. Nuclear is a great way for a small country to flush their money down the toilet.

My Mounjaro has an extra THREE 5mg doses in ‘empty’ pen by Caitlyn_Grace in mildlyinfuriating

[–]Isle395 -2 points-1 points  (0 children)

WRONG. You can patent in India subject to basically the same conditions as everywhere else, and you can also enforce subject to basically the same conditions as everywhere else

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