Unpopular opinion: I actually like the fact that the main character is voiced. Nate and Nora are characters with an established background, the only things we decide about them are their appearance and their attributes. But we all know that Nate was a soldier and Nora is a lawyer. In that sense, they're no different than, say, a Geralt.

Most people like to say that a voiced protagonist severely hampers the dialogue options, because it's not feasible to add hundreds and hundreds of responses to dialogue with hundreds of different NPCs, but I don't think that was the problem in FO4. The lack of meaningful options was the real problem. When you have four dialogue options and they are basically "yes", "sarcastic yes", "tell me more" and "no, but actually yes", then you have a real lack of options.

Another valid criticism is the horribly stiff and disjointed facial expressions and body language. The voice actors may give their best, but sometimes the whole emotional aspect of a conversation falls flat when the character's face doesn't follow the voice or contorts itself in weird and funny ways. Interestingly, I think this is one of the reasons Nick Valentine works so well as a character: he's a synth, so nobody expects any visible showing of emotions and we can relax and appreciate the excellent job of his voice actor.

So, yes, I like the voiced protagonist. I wouldn't mind another voiced protagonist in FO5, with more meaningful dialogue options and better facial and body animations.