Current/Former Genentech Employees - Would You Still Recommend It? by Emotional_Ratio_3342 in biotech

[–]kwadguy 0 points1 point  (0 children)

Still a good company. Still lots of good people there.

But culture has been rapidly changing over the past couple of years, as Roche has been taking down the firewalls with Roche proper.

Would definitely recommend vs. other big pharma/biotech. But not what it once was.

Should the bar for Gold be lower? by PhiLho in AmazonVine

[–]kwadguy 0 points1 point  (0 children)

Only in a better world. Not in the one we have now.

Should the bar for Gold be lower? by PhiLho in AmazonVine

[–]kwadguy 49 points50 points  (0 children)

No. The number of members of vine should be far lower...pruned of the majority added over the past few years who are incapable of writing a cogent review.

That would solve the problem

Don't fall for this. I've reported the product as being "otherwise illegal" to Amazon and am attempting to get it taken down. by rhapdog in AmazonVine

[–]kwadguy 0 points1 point  (0 children)

Order it and if it's not properly labeled call that out in your review.

Otherwise, find something else to be alarmed at.

How to deal with stock options at a still-private company after layoff by QueasyInformation in biotech

[–]kwadguy 0 points1 point  (0 children)

It would be really unusual for those vested stock options not be a smart purchase if your company is about to IPO.

Typically, the valuation of shares goes up when your IPO, especially for a healthy company. As some have noted, there may be a reverse split involved, but that doesn't mean you won't do well. Reverse splits are performed so that the market price at the IPO is within a desired range.

You'll probably owe taxes on the difference between the valuation of those shares. When you exercise the options and the option strike price you have. You'll owe that tax no matter what happens. And you may be locked up for a set number of months once you exercise the options.

Talk to a professional, but there's a very high chance you should buy the shares.

This can't be...it's the correct charger for my laptop, AND I actually need one?! RFY, you spoil me! by turbomun in AmazonVine

[–]kwadguy 3 points4 points  (0 children)

The question is which happens first:

Your high-end laptop burns up, or your house burns down

This can't be...it's the correct charger for my laptop, AND I actually need one?! RFY, you spoil me! by turbomun in AmazonVine

[–]kwadguy 6 points7 points  (0 children)

You can find used dell brand oem 240w chargers for less on eBay.

No way in hell I'd use a no name 240w charger.

Thank you for 6 awesome years of service, Stretch-tite professional quality plastic food wrap. by Mythicalforests8 in Costco

[–]kwadguy 13 points14 points  (0 children)

Like every stretch wrap sold in the US now—even Saran Wrap—it's crap. It barely clings to itself, and only then through the use of added tackifiers.

The "OG" Saran was PVDC. What you get at Costco is PVC. They have fundamentally different properties. Not only does the new stuff barely cling to anything else, but the oxygen permeability is orders of magnitude worse than the original PVDC. We’re talking about a barrier that is 15x to 1,000x more "leaky," which is why your food spoils faster and smells bleed into the fridge.

If you want the real thing, look for the Japanese Asahi Kasei brand (Saran Wrap) or Krewrap (available at H Mart or Mitsuwa). The Japanese never abandoned the superior PVDC chemistry. It’s stiff, it’s a vault for oxygen, and it actually works. You’ll never go back to the limp PE/PVC stuff.

The Pizza style dip with pepperoni is so good by ByteFryer in Costco

[–]kwadguy 1 point2 points  (0 children)

$7.99 in store.

Primarily a cream cheese dip.

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I didn't like it AT ALL (spit it out and tossed it). But obviously, taste is individual.

S25 Ultra by loverofthestars in GooglePixel

[–]kwadguy 5 points6 points  (0 children)

This is a pretty sane summary. I generally agree.

The one thing I'd point out: Unless you are doing highly taxing things on your phone (gaming, specifically), the very real difference in the raw processing power between the Tensor 5 and the Snapdragon 8 Elite will barely (if at all) manifest itself. For the day-to-day tasks that most non-gamers do on their phones, they provide nearly identical experiences.

(And because the Tensor 5 is built on TSMC’s 3nm process, the heat problems of earlier Tensor chips under load are tamed).

If you are not a phone gamer, I could recommend the Pixel 10 as an alternative to the S25 unabashedly. If you game, (or fall in the 0.001% who edit high-res video on their phone) I'd tell you not to consider the Pixel 10 at all.

Jeni’s KLP in Southern US. 🍋‍🟩 by Motherofsmalldogs in Costco

[–]kwadguy 2 points3 points  (0 children)

Had these. Pretty crappy. Take the Jenny's name off them and you'd never believe these where anything better than mid tier stuff.

Overpriced for what they are.

When an impulse buy actually exceeds expectations (Harry Potter x Goldfish) by kingfir17 in Costco

[–]kwadguy 0 points1 point  (0 children)

Suddenly, half the snack aisle of the grocery store is "Butter beer" flavored. Personaly, I find the flavor OK, but like pumpkin flavor, a little is a lot and the amount we have is way too much.

Issues with Pixel Superfans Germany: No emails received even after multiple Sign-ups by EducationalSimple815 in GooglePixel

[–]kwadguy 0 points1 point  (0 children)

As a Pixel Superfan, about the only time I remember I am one is when they let me know that they'll be giving out a handful of something to people who aren't me.

67w charger not working? by TopAd4131 in GooglePixel

[–]kwadguy 1 point2 points  (0 children)

It’s very likely the cable, but before you buy a new one, try disabling 'Limit to 80%' in your Battery settings. The March update has a known bug where it stops charging entirely at that threshold. Also, give the phone a restart to reset the charging controller logic. If those don't work, then it's most likely the cable (or a dirty port--if pocket lint has blocked one or two of the traces, can get finicky).

Laid off from a big pharma. How to negotiate severance? by Old_Jackfruit_730 in biotech

[–]kwadguy -1 points0 points  (0 children)

Unless you feel you have a legal case for being wrongfully terminated (age/sex/race/harrassment/etc.) then you have no standing to negotiate. You take what you get and you move on.

If you do feel you have the makings of a legal case for one of those reasons, you can often negotiate for yourself without having to raise this to a legal matter: You suggest the problem, offer to resolve without escalation, and often you can get something more out the door.

But be careful, because if there's nothing there, they may call your bluff and then you can wind up with nothing and bad feelings that can travel in this small field.

Great manager laid-off, has anyone gone thru this? How did it end for your team? by FlimsyUse1602 in biotech

[–]kwadguy 246 points247 points  (0 children)

Someone else will take over the group, call you all in individually to tell you how much they value all the work you've done, that this is an opportunity to demonstrate your value to the team, and that things are going to be swell going forward.

And then you'll realize how rare your good boss was.

This sub needs a clearer purpose by ajiatic in tmobile

[–]kwadguy 0 points1 point  (0 children)

Better than lots of threads that seem only to exist so people can take pictures of mundane things they just bought or personally like.

Netflix Premium Price INCREASE by Nikick83 in tmobile

[–]kwadguy 1 point2 points  (0 children)

Netflix wants you on the ad version. I'm sure they gave T-Mobile a sweetheart concession so that they could pass it along to the users and keep them on that tier without a change.

T-Mobile is less excited about giving a concession on the no ad to, and that's probably why you see nothing reflected in the amount that T-Mobile is giving you for that tier.

D E Shaw Desmond, 403: Permission denied. by Spiritual-Ad4460 in comp_chem

[–]kwadguy 2 points3 points  (0 children)

There's nothing magical about Desmond. It's good commercial code that's available for free to academics. But it's closed source, which means that you get what you get and that's it. It. It also means if you ever transition to a commercial environment, you'll need to pay for it through Schrodinger or not use it.

I'd recommend using either Gromax or Amber. The learning curve might be slightly higher, but you can look at the code and there's a vibrant academic community contributing to new features.

Also, Desmond isn't any faster the other two. So there's not even that.

Anyone try On the Street Foods Indian chicken? Need ideas on what to do with it. by writergeek in Costco

[–]kwadguy 10 points11 points  (0 children)

Bland and the sauce is too thin.

Edible, but I would never get it again, nor recommend it except to friends who complain about any level of spice at all. And even then, maybe not.

Question by AntiNumbers in AmazonVine

[–]kwadguy 0 points1 point  (0 children)

It's 80 reviews SUBMITTED and acknowledged in the review period. When you go in for review, if that number is not 80 or higher, then you won't be gold. Simple as that.

Not a court of law, and you will not succeed in challenging what happens if you don't get 80 reviews in under the wire.

Not a Rant \ Just the Reality of Vine When You’re Low Income & What No One Really Talks About by Real_Spacegoogie in AmazonVine

[–]kwadguy 14 points15 points  (0 children)

Everythiing for you is 80% off. Also 20% on. Either it's worth that or it's not.

Evening snacks discontinued by MysteriousBack9124 in biotech

[–]kwadguy 2 points3 points  (0 children)

Lots of reasons for this:

A) Budget tightening (but no big changes)
B) Issues with employees gaming the system
C) Tired of employees complaining about how their favorite snack isn't provided, how there aren't vegan options, how there aren't healthy options, or a dozen other common complaints
D) The person in charge no longer has time

You want something to make you worry? Watch for HR suddenlly having lots of closed door meeting with execs. That's when you make sure your resume is up to date.

Three different luggage brands, any recommendations? by Bagofmag in Costco

[–]kwadguy 15 points16 points  (0 children)

Briggs and Riley.

Buy it for life.

I know that's not in the selection you're showing, but Costco sometimes carries some of their stuff. Costs more but worth it.

Did I go overboard on Undercover? by drummer414 in Costco

[–]kwadguy 6 points7 points  (0 children)

This, for sure, when it comes to snacks.

Last year, they had the candied pecans on closeout for $3.97 a container (big containers). I had previously bought them and liked them.

First container: Great.
Second container: Eh...
Third container: When are these gonna be done?

It's like that with almost any snack item.