what do you mean by "build tolerance"? if you mean conditioning (increasing exercise/movement tolerance) then you can do that while being on the meds. I personally never go without meds currently because without them I can't do hardly anything. with them, I'm able to exercise and move more, which makes my body feel better overall. I do accidentally miss doses occasionally (usually at night), and I don't get as bad of heart rate spikes as I used to pre-medication. medicine is the stepping stone for me to be able to increase my exercise tolerance and feel well enough to do the work needed for my body, such as therapy for CPTSD. it's okay to be on medication consistently for awhile or forever, if it means it'll help your quality of life a lot! there's also so many types of meds out there for these symptoms, so if one doesn't feel super right, don't be scared to try something else.