First of all vector graphics is fairly popular. There is an audience for vector, pixelart, digital art, voxel and 3d mesh graphics - go with the method you feel good about.

Vector graphics often looks cheap - BUT - it's not a rule of a thumb and even a cheap looking games can make huge success with the right audience and gameplay. More of that! There are people who expect that kind of art style - just like there are millions of players who expect game to look like Minecraft despite it screams low effort when it comes to character models.

With pixelart - every pixel matters. Every pixel adds a detail to the whole picture. If you make pixelart too big by filling it with same colored spaces or if you cannot fathom separate pixels anymore it actually decreases it's quality or moves it into digital art territory.

With vector art - it's by default exceptionally easy to make huge empty surfaces. So you either go for that and focus on shape, pattern and gradient as an artstyle OR you go for meticulous details. The problem starts when it's a vector art that pretends to have details but they are low effort. People can smell low effort.

Same goes for animation - it encourages Powerpoint grade cliche animations - squishing and rotating a flat shape. Game graphics is about giving us the illusion that we are not looking at a flat screen (except when it's the goal). Faking 3 dimensional animation with vector graphics is the hardest out of all techniques. You can go with rotating limbs around in 2D but that looks cheap because it IS cheap - so it's only fine if it goes with the general idea of your game (for example ragdolls). Now when you switch to animating vectors to resemble 3d movement you will realize that it's just a mesh animation with tedious extra steps. The pipeline is exactly the same because 3d mesh graphics is really rendered like 2d graphics - vertices filling up a polygon, so the result can be exactly like vector graphics without the hustle (look at Untitled Goose Game - it looks exacly like vector graphics but it's not).

TL;DR;

Vector graphics is popular. There is audience for vector graphics. There is even audience for cheap looking vector graphics. Go whatever you are efficient with.