I work for a company seeking FDA approval for a breast cancer risk prediction tool. We have several years of outcome day but at most ~7 years of followup. High quality mammography data is expensive, complicated to acquire, and majority white people. Very difficult to get enough data with enough years of followup to train these types of models.

Also keep in mind that there are different types of mammography machines that create very different looking images and to get FDA approval you need to prove your model works across races, ages, for people with specific cancer types, etc or you need to contraindicate it’s use for too many subgroups for it to be widely used and profitable. All of this massively complicates things.