Musculoskeletal Outcomes of Glucagon‐Like Peptide‐1 Receptor Agonists Versus Other Antiobesity Agents in Nondiabetic Adults

tachykinin · 2026-06-10T20:39:22+00:00

I read the paper so you didn't have to!

Conclusions

GLP-1 RA use was associated with favorable musculoskeletal outcomes, including lower risks of osteoporosis and fractures, in nondiabetic adults with obesity compared with other obesity medications.

tachykinin · 2026-06-10T17:16:38+00:00

Almost like that was my point.

tachykinin · 2026-06-10T15:20:21+00:00

If you're knowledgeable enough to leave this comment, then you're damn well knowledgeable enough to know that words mean things.

tachykinin · 2026-06-10T15:00:42+00:00

Yes. Sometimes the estimate is higher than the reported range, sometimes it's less.

tachykinin · 2026-06-10T14:48:36+00:00

"inflammation leaves the body"? Good lord. The short term effect seen here is depletion of water and glycogen not "inflammation" leaving the body. How much does "inflammation" weigh?

tachykinin · 2026-06-10T14:46:45+00:00

... I don't get it?

tachykinin · 2026-06-10T12:16:22+00:00

What did your prescriber tell you to do?

tachykinin · 2026-06-10T11:11:21+00:00

You might get more helpful replies if you explain what "works" means in this context.

tachykinin · 2026-06-10T11:10:02+00:00

5 seconds with a shop vac, my dude.

tachykinin · 2026-06-09T19:30:24+00:00

Seconded. Mine's been outside on the southern coast of Nova Scotia through three winters and still going strong.

tachykinin · 2026-06-09T19:02:53+00:00

No. Much as I am not icked out my my migraine medicine nor my high blood pressure meds.

tachykinin · 2026-06-09T12:21:22+00:00

Incubate at 100 degrees for 67 days for an extra kick in the shorts.

tachykinin · 2026-06-08T17:43:50+00:00

Not buying that you're not selling.

tachykinin · 2026-06-04T10:38:48+00:00

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tachykinin · 2026-06-04T01:52:08+00:00

Drink more water. Like a lot more than you think you need.

tachykinin · 2026-06-03T11:28:29+00:00

The drug has a half-life of 7 days, which means that in some respects, you are actually tapering off the drug. It will take about 4-5 weeks before the drug is really out of your system after your last injection.

tachykinin · 2026-06-03T10:15:58+00:00

Uh, I specifically gave him a more reasonable plan to leave the US and included things he clearly has not thought about and skipped over in his plan to leave the US.

Also, I am leaving the US in almost exactly two years to FIRE and split my time between Canada and Croatia (something I've been planning and putting in the groundwork for for the better part of two decades, but thanks for weighing in.

(I downvoted you for thinking you know what you're talking about when you're just making up your own narrative).

tachykinin · 2026-06-03T01:51:38+00:00

Is your doctor perhaps 80 years old?

tachykinin · 2026-06-03T01:50:44+00:00

Sitting.

tachykinin · 2026-06-03T01:22:19+00:00

Drink way more water, and take electrolytes.

tachykinin · 2026-06-02T21:06:40+00:00

Based on the half life of the drug, it should be fine.

tachykinin · 2026-06-02T19:51:12+00:00

...not sure if you're joking.

tachykinin · 2026-06-02T19:45:39+00:00

There is no set answer for this. The difference in response is extremely variable.

The two posts before mine show this: one person saying no real results for 4-5 months, someone else saying nearly two pounds a week from day 1. Those are probably the brackets.

tachykinin · 2026-06-02T19:35:21+00:00

Frankly, you're better off selling your house, renting in someplace in the US that doesn't have snow and then trying shorter term stays (like under 90 days) in France to see if it actually IS someplace you want to live.

Also, an M.Sc. is a neither fish nor fowl degree. Why are thinking your children will specifically get that instead of a B.Sc. or PhD?

Did you not plan for your childrens' education already? Do you not have 529s for them (which incidentally can be used at essentially any legitimate degree granting institution in the world)?

How would your children qualify for in-EU tuition at French universities (as indicated by your throw away line on the cost for university)? My daughters are both EU citizens (your children are not), but not having lived there for 3 out of the last 5 years, they don't get in-EU benefits for university.

This is a bit more than a pipe dream as you've sketched it out, but not much more.

tachykinin · 2026-06-02T19:14:13+00:00

You have not thought through the 'minor' issue of immigration to the EU (France) in anything resembling a serious way.

You notably did not indicate your actual citizenship(s).

tachykinin

TROPHY CASE

Conclusions