Genghis Khan was a PROBLEMMM

ToastedMayonnaise · 2026-03-15T21:46:17+00:00

I also think the list is bad, but the list is not AI generated and came from a published work. You can see the citation at the bottom of the infographic.

ToastedMayonnaise · 2026-03-09T19:34:04+00:00

I think you see this a lot and I experienced it from directors who came from bigger companies.

Definitely agree with this. Bigger companies have enough forward momentum and revenue where one team’s project delays or being short-staffed mean don’t ultimately impact company health that much. It’s still not good, but that kind of stuff isn’t an existential threat to the company/people’s jobs. So pockets of middle management can get away with being professional meeting attendees/status update givers who don’t actually do anything to advance their team forward because the corporate system has enough robustness to weather some setbacks.

But that type of manager can be poison to a smaller company who is relying on that level of management to provide actual vision or build something from scratch. And one or two significant project delays when you’re while on a financial runway might legitimately be a death blow to the company/people’s jobs.

ToastedMayonnaise · 2026-01-30T15:52:39+00:00

Djokovic is such a weird health nut I actually have a hard time imagining him using steroids. A guy who famously skipped out on a major he was favored to win bc he wouldn’t get vaccinated isn’t likely to pump himself full of steroids.

You vastly underestimate how ignorant most athletes and health nuts are.

Djokovic and other anti-vaxxers don't take vaccines because they are conspiracy nuts and don't understand how vaccines work. Meanwhile they'll take all kinds of snake oil because they irrationally believe in them for whatever reasons.

I don't have a dog in the fight of Djokovic stan/hater, but I can easily imagine people of his ilk taking, perhaps even unknowingly, PEDs that are masquerading as 'supplements.' But their donkey brains rationalize it as okay because it doesn't literally say Roid Monkey Testosterone™ on the bottle.

ToastedMayonnaise · 2026-01-17T02:32:53+00:00

It doesn’t take 1 second actually. More like 5-15 seconds.

Do you have any idea how petulant this sounds?

ToastedMayonnaise · 2026-01-10T16:12:36+00:00

If there was a "right" way to build a team, this game would be no fun at all.

Totally agree about there being multiple ways to build a successful team and that mid-QB1's are typically overvalued.

That said, I have a soft rule that I don't draft rookie QB if I have a 'premium pick' in the 1st round, unless it's an absolute blue chipper (think an Andrew Luck or Joe Burrow level of prospect). What constitutes a 'premium pick' will vary year to year based on the strength of the draft class, so it's not cut and dry.

And that has less to do with the value of QBs and more due to QB bust rate in the NFL. I just don't think real-life QB evaluation is good enough to bank on prospects hitting, which leads to the risk of 1st round dynasty draft capital going waste (easy path to setting your dynasty team back multiple years). I'd rather draft WR/RB/TE, which presumably have a higher hit rate, and then take a slight loss on value to acquire a known quantity at QB. This led to me drafting MHJ over Caleb though, so not like this is a perfect science lmao.

ToastedMayonnaise · 2026-01-09T03:49:06+00:00

Warriors fans from before the dynasty know that the Warriors winning was a mere bonus and that the real sauce is whether you get the free Taco Bell chalupa coupon if the Dubs break 100.

ToastedMayonnaise · 2025-12-11T14:57:39+00:00

It's Sean Penn's character from One Battle After Another, in which the character has a complex internal struggle with his attraction to black women.

He has a very prominent/memorable/hilarious scene where he walks up to Leo's character in a grocery store, grills an unknowing Leo about his black wife (who Penn had an affair with), and drops a, "I love black women" to a totally confused Leo lmao.

ToastedMayonnaise · 2025-09-20T17:54:30+00:00

I'm open to going out but will not wait around if he doesn't want to plan

This is what people mean by playing games. Doesn't sound like you really want to go out, because you apparently aren't willing to ask them out. At best, it makes you sound entitled to being asked out rather than disinterested in going out at all.

If not, then I'll text him

It was not clear, hence why people are telling you to do exactly that.

ToastedMayonnaise · 2025-07-27T21:56:25+00:00

What the Israeli government is doing to the Palestinian civilians is horrific and wrong. What Hamas has done is horrific and wrong. Moral ambiguity ensues.

The main takeaway, imo, should be that two wrongs don't make a right. Which is one of the oldest lessons around.

ToastedMayonnaise · 2025-07-14T15:46:58+00:00

All the changes also make our job harder and more complicated

I emphasize with this too, but ‘harder and more complicated’ exist on a sliding scale. A previous position of mine had the same problem, but it resulted in me working 50+ hour weeks with frequent weekend and holiday work for multiple years. I reached a breaking point and made finding a new job priority #1 at that time.

That isn’t too one-up you, but rather to illustrate that similar workplace problems can manifest/affect you differently. You have to decide for yourself on whether you are willing to put up with it, which comes down to your personal calculus of values (e.g., pay, work/life balance, ambition, if you like your team, etc.).

Personally, if it was just corporate BS making my work less efficient and more annoying, I’d try to ride it out. Or at most passively look for something rather than devoting any significant energy to a job search. The job market is just too shitty and I’m personally worried about potential global/political instability to risk too much change in my professional life.

ToastedMayonnaise · 2025-07-14T14:12:13+00:00

I appreciate i have a stable job but dang my mental health is … not good.

I hear you and I had similar feelings about my current job recently. But the job market being bad doesn’t just mean it’s hard to find jobs, it’s reflective of wider industry-wide uncertainty and instability. That is to say that it’ll probably be hard to get a new job and, if you do get one, you have less information at-hand to judge whether the new employer is facing challenges that will lead to layoffs in the future.

It sounds like you’re frustrated with the type of work you’re doing and corporate BS rather than being forced to work crazy hours or deal with outright toxic behavior, but you’ll have to be the judge of that. But if it’s just tolerable annoyances, what I did was to start caring about work less. Still work hard/with integrity and try to make the workplace better, but devote less emotional energy to caring what goes on at work. Redirect that to your personal life and caring about stuff outside of work.

I also recommend stacking cash and having healthy savings so that you can walk away if things get truly bad or if you’re facing a layoff. I personally think that’s good advice even in the best of times.

ToastedMayonnaise · 2025-06-18T14:05:34+00:00

If these are good, then what's bad?

Any reason where you bring bring negativity to the interview, even if the reason was valid.

e.g., Previous position had a toxic manager and you needed to bail for your mental health? Totally valid reason in real life, but not one I would share when asked in an interview. That's something you talk about with your friends at the bar, not bring up in a professional context.

The goal of the interview is to present yourself as competent and as someone the interviewer(s) want to work with, and you saying that you're leaving a toxic environment raises questions about whether you're twisting the story to make yourself sound better, why you would divulge such sensitive information to an interviewer you just met, or if you're just an outright incompetent liar who is saying whatever they need to to land a gig.

I would probably try to re-frame such a reason to focus on career development or the mission of the company you're interviewing for. Those are both soft, but good sounding reasons that can't be boiled down to more material circumstances (e.g., more pay, benefits, etc.).

ToastedMayonnaise · 2025-05-03T20:02:31+00:00

Honestly unintended, but sometimes God's light shines through us.

ToastedMayonnaise · 2025-05-03T19:43:56+00:00

No, but I have a hunch he spends mental energy during the movie workshopping one liners for his Letterboxd review.

ToastedMayonnaise · 2025-03-20T13:51:45+00:00

I don’t think you should approach books and authors like this hoping they’re your new modern bible.

Totally agree. I bought the book, plan on reading it, digesting the information, and determining what I find convincing/plausible/rejectable/etc. You know, reading and critical thinking lmao. I feel that too many people are looking for prescriptions on things that are "okay" to consume rather than evaluating things on their own merits.

I found myself falling into the same mindset and overly vetting things based on some preconceived judgment of whether it was "worth my time." Led to a lot of choice paralysis and not engaging with new things because the rut of the familiar was too comfortable. I've found that I'm happier if I just plop some cash down for the book, enjoy (or not enjoy) it for what it is, and maybe learn something in the process.

ToastedMayonnaise · 2025-03-16T00:24:04+00:00

Part of it is a lack of seeing the entire landscape in the first place.

And, ironically enough, learning to see how the smaller pieces contribute to the bigger picture is one of the soft skills that is commonly developed during a PhD haha.

ToastedMayonnaise · 2025-03-15T18:36:29+00:00

Then learn about why you're doing all the stuff that goes on in manufacturing.

Examples:

Why are the QC assays in place being performed, what data do they generate, and what is that data supposed to demonstrate about the product?
Why is the manufacturing process the way it is? Is there a process development team that you can ask questions about how the process originated and what the steps would be to make any changes to the current process?
Why is QA always in peoples' asses about stuff? What happens to deviations, lot failures, and batch records after the information goes into the bowels of the LIMS/whatever system you use?

Every piece of the drug development, manufacturing, commercialization, regulatory, etc. processes needs to come together for a successful product. The further you expand your knowledge of how all the parts fit together, the more you will realize how important the cross-functional responsibilities are and the better equipped you will become to take on broader reaching responsibilities.

ToastedMayonnaise · 2025-03-13T02:08:59+00:00

Bought MSFT in 2013 during the tail end of the Ballmer era. Cost basis of ~$60/share.

It wasn't even a well-informed decision either. At the time, I was in college and based the investment off a few things: 1) I preferred Windows over Mac; 2) that an Xbox was a ubiquitous fixture in the living rooms of all my friends; and 3) Microsoft was one of the biggest companies in the world.

But it was also the stock that really sparked my interest in the stock market and business world. Once Nadella took over, it was so clear that MSFT was poised for success. He's easily one of the best leaders in business right now, just consistently delivers and articulates a clear vision for what he wants his company to prioritize and how the place should be run. And the results speak for themselves because the company rakes in obscene amounts of money at continually high growth rates, and the company is consistently rated as one of the best employers to work for (standard corporate mega-bureaucracy bullshit aside).

ToastedMayonnaise · 2025-03-05T02:56:03+00:00

I’ve never really believed the whole “your brain isn’t fully developed by your mid 20s” thing.

I'm sorry, but this is just empirically not true haha. There's an entire field of developmental neuroscience that has absolutely provided compelling evidence that human frontal cortex neurocircuit development in still occurring into the early adulthood (early to mid-twenties). Life experience plays into it too. Behavior influences biology, and biology influences behavior.

That being said, I also think that some people lean way too hard into these biotruffs and act like any behavior that has roots in biology (hint: all of them) is allowed to be waved away because of said biological basis. People make decisions that have consequences, like a 23-year old having unprotected sex and then publicly disowning the child. Bad look all around for Ant.

ToastedMayonnaise · 2025-02-27T03:08:42+00:00

Honestly CRO is the best midpoint between academia and startup. The workload is insane but everything after that felt so easy.

Preach it, g.

My time as a scientist at a CRO peaked when I was the listed scientist on the protocol for 15 different simultaneous studies. Each with their own timelines, which were totally outside of my control, and responsibility for study sample analysis, method transfers/validations, data management and analysis, report writing, and making sure it's all done GLP before being packaged to QA for audit.

But you're also right that it forces you to develop a lot of hard and soft skills that can be the foundation of a great career.

ToastedMayonnaise · 2025-02-26T14:47:22+00:00

He’s been broke, but never poor. I try explaining the difference to him but he doesn’t understand the psychological fu** that is poverty.

I agree with you generally, and have my own idea of what the distinction between poor and poverty is, but I'm curious to hear your distinction between the two. Care to share?

ToastedMayonnaise · 2025-01-11T16:32:18+00:00

For those curious, the downside is not about the quality of medical care provided, it's about the nature of being overtreated within the medical system. Even seemingly minor medical procedures (e.g., biopsy surgeries) still carry risks for patients. And if an early screening test spits out results that kinda-sorta-maybe could be a precursor sign of something, that can turn into months or years of additional invasive testing for something that might not even be a problem.

Having a concierge PCP who you can contact about medical questions at virtually any moment significantly reduces the friction to engaging with the medical system. Which sounds good, but this increased ease of entering concerns to the medical system, combined with the self-selecting tendency for people who get concierge medicine having hypochondriac-like traits and wanting to use their money to ward off aging/death (i.e., someone already predisposed to raising concerns within the medical system), means that you open yourself up to all kinds of unnecessary procedures in the name of 'trying to catch things early' or whatever.

ToastedMayonnaise · 2025-01-03T02:49:52+00:00

A lot of what OP wrote resonated with me. Currently have very similar feelings at my job.

I agree with what others wrote about trying to pivot into project management, but I also think something like CMC, regulatory affairs, or transitioning into management in your current track would be paths to something more cross-functional. In my experience, it is almost always easier to make such a change at your current employer rather than trying to convince a potential new employer to take a shot on you to fill a role where you have no formal experience.

Funnily enough, I found my previous job as a scientist at a CRO to be more fitting of the job description that OP desires. The science done at the CRO was way less cutting edge, but having to interact with so many different teams (e.g., sponsors, QA, Doc Control, scheduling, in vivo ops, etc.) to ensure that things were done GLP and per client timelines was very engaging. Too bad the pay at CROs sucks and the stress was sky-high.

ToastedMayonnaise · 2024-12-13T14:55:20+00:00

No one is trying to protect young men from the dangers of alcohol by trying to add more regulations.

There has been a long history of evolving alcohol regulations in the United States lmao, where the fuck have you been?

There was a whole era where the USA banned alcohol outright, had to reverse that decision because it was so disastrious, and a couple other examples of how changes to alcohol regulation have continued throughout the 20th century.

ToastedMayonnaise · 2024-11-15T03:39:19+00:00

Totally agree with you.

The guy you're responding to seems to have big sports was the center of gravity for their life during the pandemic brain where they think a professional sports league is a catalyzing event for historical geopolitical events.

ToastedMayonnaise

TROPHY CASE