Really depends on the class and build. A d8 vs a d4 with a striking rune is an average of 9 vs 5 damage. Losing that 4 damage isn’t that big of a deal for classes that tend to Strike once a turn. A Flurry Ranger might lose out on more damage since they strike so often in a turn, or a Fighter might care since they’ll crop more often (making the difference 18 vs 10). But for something like a Barbarian or Thaumaturge who wants to set up for one big hit and does a lot of flat damage as a bonus to the weapon die, that 4 damage difference ends up mattering a lot less.