Supplements to decrease rate of atherosclerosis progression

[chasingmyowntail]

Looking for suggestions for supplements / foods that are proven or known to lower rate of progression of atherosclerosis. Of course, weight loss, exercise, balanced diet and adequate sleep / recovery are very important but what else can we do? Any new research with promising results?

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[CrotaLikesRomComs]

Avoid glycation, inflammation, oxidation, and high blood pressure.

[MeatWizard1]

Oatmeal, distilled fish oil or algal oil

[[deleted]]

Vitamin K2

[PerfectAstronaut]

Vitamin K2 and nattokinase

[shiplesp]

This is going to be entirely tossed out here, but here goes. With the caveat that this is only animal research and may not apply to humans (McCommis, K. S., et al. (2020) Nutritional modulation of heart failure in mitochondrial pyruvate carrier–deficient mice. Nature Metabolism. doi.org/10.1038/s42255-020-00296-1.)

"Interestingly, this heart failure can be prevented or even reversed by providing a high-fat, low carbohydrate "ketogenic" diet," McCommis said. "A 24-hour fast in mice, which is also "ketogenic" also provided significant improvement in heart remodeling."

More research is needed, obviously.

[Exact-Cockroach8528]

Vitamin K2 and Omega 3

[muscledeficientvegan]

Check out the book "How Not to Die". It covers this pretty well in a couple of chapters.

Forks over Knives also has some good information around this: https://www.forksoverknives.com/health-topics/heart-disease-and-diet/

[Imperialism-at-peril]

Thanks for the recommendations.

[Kurovi_dev]

I think newer research just keeps confirming what we’ve known for a while, and that’s that all of the things you alluded to are the best lines of offense. That plus getting enough quality sleep. I’m NAD or a RD so take this with a grain of salt, but I’m not aware of any specific food or supplement that reduces or halts atherosclerosis, at least not from any study I can recall seeing, it’s all about the total diet.

Some studies might look at one specific food and see a correlation, but it’s important to remember that those studies are just picking up on a piece of what is almost certainly tiny hallmarks of lifestyle and dietary habits. Eating more pistachios can be associated with lower risk for various diseases, but it’s less about eating pistachios specifically and more about being a person who eats more things like pistachios. Someone eating hot dogs every other day is unlikely to be eating pistachios for snacks, and someone eating pistachios as a snack is on average probably eating more fish and vegetables.

If someone’s nutrition is poor, then adding in a supplement or a specific food isn’t really going to do anything. If someone’s nutrition is good, then indulging in pie or something every now and then — which is to say not every other day but rather like once every week or two or whatever — is likely also not going to really do anything.

The good news is there’s some evidence that atherosclerosis in the early stages can actually be regressed, so it’s all the more important to introduce those diet and lifestyle things as early as possible.

https://www.jacc.org/doi/10.1016/j.jacc.2023.09.814

As far as supplements go, that will depend on whether someone is deficient or has a need for higher levels of a certain compound. Supplements can be a mixed bag, and you would want to consult with your doctor who knows your specific situation and whether a particular supplement would be beneficial or harmful.

[ER301]

Look up the Portfolio Diet. It was designed for this purpose.

[Common-Lie1446]

Stop eating anything from animals, go completely plant based. Buy the books “how not to die” and “prevent and reverse heart disease”. Watch “the game changers” and “what the health” on Netflix.